The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Protein-arginine deiminase, N-terminal domain
".
FunFam 3: Protein-arginine deiminase type-4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 15 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-arginine deiminase activity GO:0004668
Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3.
|
4 | O88807 (/IDA) Q53HY9 (/IDA) Q9UM07 (/IDA) Q9Z183 (/IDA) |
|
Protein-arginine deiminase activity GO:0004668
Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3.
|
2 | Q9UM07 (/TAS) Q9Z183 (/TAS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | O88807 (/ISS) Q9Z183 (/ISS) |
|
Protein-arginine deiminase activity GO:0004668
Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3.
|
1 | Q9UM07 (/IMP) |
|
Protein-arginine deiminase activity GO:0004668
Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3.
|
1 | Q9Z183 (/ISO) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9UM07 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9UM07 (/IMP) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q9Z183 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9UM07 (/IPI) |
|
Arginine deiminase activity GO:0016990
Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.
|
1 | Q9UM07 (/IDA) |
|
Arginine deiminase activity GO:0016990
Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.
|
1 | Q9Z183 (/ISO) |
|
Arginine binding GO:0034618
Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid.
|
1 | Q9UM07 (/IMP) |
|
Arginine binding GO:0034618
Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid.
|
1 | Q9Z183 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9UM07 (/IMP) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9Z183 (/ISO) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein citrullination GO:0018101
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.
|
3 | O88807 (/IDA) Q53HY9 (/IDA) Q9UM07 (/IDA) |
|
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
|
2 | O88807 (/ISS) Q9UM07 (/ISS) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
2 | O88807 (/ISS) Q9UM07 (/ISS) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | O88807 (/ISS) Q9UM07 (/ISS) |
|
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
2 | O88807 (/ISS) Q9UM07 (/ISS) |
|
Histone H3-R26 citrullination GO:0036413
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.
|
2 | O88807 (/ISS) Q9Z183 (/ISS) |
|
Histone citrullination GO:0036414
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein.
|
2 | Q9UM07 (/IDA) Q9Z183 (/IDA) |
|
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
|
1 | Q9Z183 (/IMP) |
|
Chromatin organization GO:0006325
Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
|
1 | Q9UM07 (/TAS) |
|
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
|
1 | Q9Z183 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | Q9Z183 (/IMP) |
|
Cellular protein modification process GO:0006464
The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
|
1 | Q9UM07 (/TAS) |
|
Protein citrullination GO:0018101
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.
|
1 | Q9UM07 (/IMP) |
|
Protein citrullination GO:0018101
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.
|
1 | Q9Z183 (/ISO) |
|
Arginine deiminase pathway GO:0019546
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
|
1 | Q9UM07 (/IMP) |
|
Arginine deiminase pathway GO:0019546
The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
|
1 | Q9Z183 (/ISO) |
|
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
1 | Q9Z183 (/IMP) |
|
Histone H3-R26 citrullination GO:0036413
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.
|
1 | Q9UM07 (/IDA) |
|
Histone H3-R26 citrullination GO:0036413
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.
|
1 | Q9Z183 (/ISO) |
|
Histone citrullination GO:0036414
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein.
|
1 | Q9Z183 (/ISO) |
|
Histone citrullination GO:0036414
The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein.
|
1 | O88807 (/ISS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | O88807 (/ISS) Q9Z183 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9UM07 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9Z183 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q9UM07 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9UM07 (/TAS) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q9UM07 (/IMP) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q9Z183 (/ISO) |
