The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Aminopeptidase N

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Aminopeptidase activity GO:0004177
Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
45 O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA)
(35 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI)
(9 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
19 P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI) P04825 (/IPI)
(9 more)
Metalloexopeptidase activity GO:0008235
Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
10 Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q60AS1 (/ISS) Q87YK7 (/ISS) Q87YK7 (/ISS) Q87YK7 (/ISS)
Aminopeptidase activity GO:0004177
Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
1 Q83EI2 (/ISS)
Metalloaminopeptidase activity GO:0070006
Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
1 Q5E5B9 (/IDA)
Metalloaminopeptidase activity GO:0070006
Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
1 Q5E5B9 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
25 Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q48FU2 (/ISS) Q60AS1 (/ISS) Q83EI2 (/ISS) Q87YK7 (/ISS) Q87YK7 (/ISS)
(15 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
19 P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP) P04825 (/IMP)
(9 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
13 O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA)
(3 more)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 F4I3R1 (/IEP)

There are 11 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
27 O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA) O96935 (/IDA)
(17 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
13 Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA)
(3 more)
Microneme GO:0020009
A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.
13 Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA)
(3 more)
Food vacuole GO:0020020
Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.
13 Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA) Q8IEK1 (/IDA)
(3 more)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 F4I3R1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 F4I3R1 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 F4I3R1 (/IDA)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 F4I3R1 (/IDA)
Chloroplast stroma GO:0009570
The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
1 F4I3R1 (/IDA)
Chloroplast envelope GO:0009941
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
1 F4I3R1 (/IDA)
Apoplast GO:0048046
The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
1 F4I3R1 (/IDA)
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