The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Transthyretin/hydroxyisourate hydrolase domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 9: 5-hydroxyisourate hydrolase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hydroxyisourate hydrolase. [EC: 3.5.2.17]
5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro- 1H-imidazole-5-carboxylate.
  • The reaction is the first stage in the conversion of 5-hydroxyisourate into (S)-allantoin.
  • This reaction will also occur spontaneously, but more slowly.
16 A0A162QLN0 A0A162QLN0 A0A162QLN0 A0A162QLN0 A0A1B2AYU5 A0A1B2AYU5 A0A1B2AYU5 A0A1B2AYU5 L8AUN3 L8AUN3
(6 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...