The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
C2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 51: Synaptotagmin 11

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 25 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P50232 (/IPI) Q9BT88 (/IPI) Q9H2B2 (/IPI) Q9H2B2 (/IPI) Q9H2B2 (/IPI) Q9R0N3 (/IPI)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
2 P50232 (/IPI) Q9R0N3 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P50232 (/IDA) Q9R0N3 (/IDA)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
1 P50232 (/IDA)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
1 P40749 (/ISO)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
1 P50232 (/IDA)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
1 P40749 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P40749 (/IDA)
Calcium-dependent phospholipid binding GO:0005544
Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
1 P40749 (/IDA)
Syntaxin-1 binding GO:0017075
Interacting selectively and non-covalently with the SNAP receptor syntaxin-1.
1 P50232 (/IPI)
Showing 1 to 10 of 25 entries

There are 69 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Negative regulation of catecholamine secretion GO:0033604
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.
4 P50232 (/IGI) Q9H2B2 (/IGI) Q9H2B2 (/IGI) Q9H2B2 (/IGI)
Negative regulation of calcium ion-dependent exocytosis GO:0045955
Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.
3 Q9H2B2 (/NAS) Q9H2B2 (/NAS) Q9H2B2 (/NAS)
Positive regulation of calcium ion-dependent exocytosis GO:0045956
Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis.
3 Q9H2B2 (/NAS) Q9H2B2 (/NAS) Q9H2B2 (/NAS)
Positive regulation of dendrite extension GO:1903861
Any process that activates or increases the frequency, rate or extent of dendrite extension.
3 Q9H2B2 (/IDA) Q9H2B2 (/IDA) Q9H2B2 (/IDA)
Regulation of endocytosis GO:0030100
Any process that modulates the frequency, rate or extent of endocytosis.
2 P40749 (/IMP) P50232 (/IMP)
Regulation of vesicle fusion GO:0031338
Any process that modulates the frequency, rate or extent of vesicle fusion.
2 P40749 (/IMP) P50232 (/IMP)
Regulation of phagosome maturation GO:1905162
Any process that modulates the frequency, rate or extent of phagosome maturation.
2 Q9BT88 (/IC) Q9R0N3 (/IC)
Plasma membrane repair GO:0001778
The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.
1 Q9R0N3 (/IMP)
Plasma membrane repair GO:0001778
The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.
1 Q9BT88 (/ISS)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
1 P40749 (/IDA)
Showing 1 to 10 of 69 entries

There are 85 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P40749 (/IDA) Q9H2B2 (/IDA) Q9H2B2 (/IDA) Q9H2B2 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
4 O08835 (/IDA) P40749 (/IDA) P50232 (/IDA) Q9BT88 (/IDA)
Integral component of Golgi membrane GO:0030173
The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 Q9H2B2 (/NAS) Q9H2B2 (/NAS) Q9H2B2 (/NAS)
Integral component of synaptic vesicle membrane GO:0030285
The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 Q9H2B2 (/NAS) Q9H2B2 (/NAS) Q9H2B2 (/NAS)
Dense core granule membrane GO:0032127
The lipid bilayer surrounding a dense core granule.
3 Q9H2B2 (/NAS) Q9H2B2 (/NAS) Q9H2B2 (/NAS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
3 Q9H2B2 (/IDA) Q9H2B2 (/IDA) Q9H2B2 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 P40749 (/IDA) P50232 (/IDA)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
2 O08835 (/IDA) P50232 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P40749 (/NAS) P50232 (/NAS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 O08835 (/IDA) P40749 (/IDA)
Showing 1 to 10 of 85 entries
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