The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
C2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 228: Blast:Protein kibra

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9VFG8 (/IPI) Q9VFG8 (/IPI)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
7 B3LWS4 (/ISS) B3P3M8 (/ISS) B4HEJ6 (/ISS) B4K6I9 (/ISS) B4M5X4 (/ISS) B4NAD3 (/ISS) B4PSQ2 (/ISS)
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
2 Q9VFG8 (/IGI) Q9VFG8 (/IGI)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
2 Q9VFG8 (/IMP) Q9VFG8 (/IMP)
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
2 Q9VFG8 (/IGI) Q9VFG8 (/IGI)
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
2 Q9VFG8 (/IMP) Q9VFG8 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 Q9VFG8 (/IMP) Q9VFG8 (/IMP)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
2 Q9VFG8 (/IMP) Q9VFG8 (/IMP)
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
2 Q9VFG8 (/IMP) Q9VFG8 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
Kibra-Ex-Mer complex GO:0036375
An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
Kibra-Ex-Mer complex GO:0036375
An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.
2 Q9VFG8 (/IPI) Q9VFG8 (/IPI)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
Cytoplasmic side of apical plasma membrane GO:0098592
The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.
2 Q9VFG8 (/IDA) Q9VFG8 (/IDA)
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