The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
NDT80 DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Meiosis-specific transcription factor NDT80

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
6 P38830 (/IDA) P38830 (/IDA) P38830 (/IDA) P38830 (/IDA) P38830 (/IDA) Q5ACU9 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
6 P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) Q5ACU9 (/IMP)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
5 P38830 (/HDA) P38830 (/HDA) P38830 (/HDA) P38830 (/HDA) P38830 (/HDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 Q5ACU9 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q5ACU9 (/IDA)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
6 P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) Q5ACU9 (/IMP)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
5 P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) P38830 (/IMP) P38830 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 Q5ACU9 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q5ACU9 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q5ACU9 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 Q5ACU9 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q5ACU9 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q5ACU9 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to stress GO:0036003
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
1 Q5ACU9 (/IMP)
Filamentous growth of a population of unicellular organisms in response to chemical stimulus GO:0036171
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
1 Q5ACU9 (/IMP)
Filamentous growth of a population of unicellular organisms in response to pH GO:0036177
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
1 Q5ACU9 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 Q5ACU9 (/IMP)
Regulation of carbohydrate utilization GO:0043610
Any process that modulates the frequency, rate or extent of carbohydrate utilization.
1 Q5A6P1 (/IMP)
Single-species biofilm formation on inanimate substrate GO:0044011
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
1 Q5ACU9 (/IMP)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 Q5ACU9 (/IMP)
Cellular response to lithium ion GO:0071285
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
1 Q5ACU9 (/IMP)
Cellular response to N-acetyl-D-glucosamine GO:0097316
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.
1 Q5ACU9 (/IMP)
Regulation of single-species biofilm formation on inanimate substrate GO:1900231
Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
1 Q5ACU9 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus GO:1900439
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
1 Q5ACU9 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900445
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1 Q5ACU9 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to pH GO:1900743
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
1 Q5ACU9 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear chromosome GO:0000228
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
5 P38830 (/IDA) P38830 (/IDA) P38830 (/IDA) P38830 (/IDA) P38830 (/IDA)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
1 Q5ACU9 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5ACU9 (/IC)
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