The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 712: Poliovirus receptor homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P15151 (/IPI) P32507 (/IPI) Q92692 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
3 P15151 (/IPI) P32507 (/IPI) Q92692 (/IPI)
Coreceptor activity GO:0015026
Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
1 Q92692 (/TAS)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
1 P15151 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q92692 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P32507 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P32507 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P32507 (/ISO)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
1 P32507 (/ISO)

There are 36 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860
Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2 P15151 (/IMP) Q92692 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
2 P32507 (/IDA) Q92692 (/IDA)
Adherens junction organization GO:0034332
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
2 P15151 (/TAS) Q92692 (/TAS)
Susceptibility to natural killer cell mediated cytotoxicity GO:0042271
The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.
2 P15151 (/IMP) Q92692 (/IMP)
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
2 P15151 (/IMP) Q92692 (/IMP)
Regulation of immune response GO:0050776
Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
2 P15151 (/TAS) Q92692 (/TAS)
Susceptibility to T cell mediated cytotoxicity GO:0060370
The process of causing a cell to become susceptible to T cell mediated cytotoxicity.
2 P15151 (/IDA) Q92692 (/IDA)
Acrosome assembly GO:0001675
The formation of the acrosome from the spermatid Golgi.
1 P32507 (/IMP)
Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002860
Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
1 P32507 (/ISO)
Positive regulation of immunoglobulin mediated immune response GO:0002891
Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
1 Q92692 (/IMP)
Positive regulation of immunoglobulin mediated immune response GO:0002891
Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
1 P32507 (/ISO)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 P32507 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
1 P32507 (/ISO)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
1 P32507 (/IMP)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
1 Q92692 (/ISS)
Spermatid nucleus differentiation GO:0007289
The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.
1 P32507 (/IMP)
Fertilization GO:0009566
The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
1 P32507 (/IMP)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
1 Q92692 (/IDA)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
1 P32507 (/ISO)
Sperm mitochondrion organization GO:0030382
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.
1 P32507 (/IMP)
Cell part morphogenesis GO:0032990
The process in which the anatomical structures of a cell part are generated and organized.
1 P32507 (/IMP)
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
1 Q92692 (/IMP)
Positive regulation of mast cell activation GO:0033005
Any process that activates or increases the frequency, rate, or extent of mast cell activation.
1 P32507 (/ISO)
Susceptibility to natural killer cell mediated cytotoxicity GO:0042271
The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.
1 P32507 (/ISO)
Adhesion of symbiont to host GO:0044406
The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q92692 (/IDA)
Adhesion of symbiont to host GO:0044406
The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 P32507 (/ISO)
Cilium organization GO:0044782
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 P32507 (/IMP)
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
1 P32507 (/ISO)
Regulation of viral entry into host cell GO:0046596
Any process that modulates the frequency, rate or extent of the viral entry into the host cell.
1 Q92692 (/IDA)
Regulation of viral entry into host cell GO:0046596
Any process that modulates the frequency, rate or extent of the viral entry into the host cell.
1 P32507 (/ISO)
Coreceptor-mediated virion attachment to host cell GO:0046814
The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.
1 Q92692 (/IDA)
Coreceptor-mediated virion attachment to host cell GO:0046814
The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.
1 P32507 (/ISO)
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
1 Q92692 (/IDA)
Positive regulation of T cell receptor signaling pathway GO:0050862
Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
1 P32507 (/ISO)
Establishment of mitochondrion localization GO:0051654
The directed movement of the mitochondrion to a specific location.
1 P32507 (/IMP)
Susceptibility to T cell mediated cytotoxicity GO:0060370
The process of causing a cell to become susceptible to T cell mediated cytotoxicity.
1 P32507 (/ISO)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 P15151 (/TAS) Q92692 (/TAS)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 P32507 (/IDA) Q92692 (/IDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
2 P15151 (/HDA) Q92692 (/HDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 P15151 (/IDA) Q92692 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P15151 (/IDA) Q92692 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P15151 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P15151 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P32507 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
1 P32507 (/ISO)
Zonula adherens GO:0005915
A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
1 P32507 (/IDA)
Zonula adherens GO:0005915
A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
1 Q92692 (/ISS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 P32507 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P32507 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 P15151 (/TAS)
Apical junction complex GO:0043296
A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
1 P32507 (/IDA)
Cell-cell contact zone GO:0044291
Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
1 P32507 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q92692 (/HDA)
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