The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 611: Tenascin C
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
2 | P24821 (/RCA) Q80YX1 (/RCA) |
Fibronectin binding GO:0001968
Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
|
1 | Q80YX1 (/ISO) |
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
|
1 | P24821 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P24821 (/IPI) |
Syndecan binding GO:0045545
Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
|
1 | P24821 (/IDA) |
Syndecan binding GO:0045545
Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
|
1 | Q80YX1 (/ISO) |
There are 35 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Neural crest cell migration GO:0001755
The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
|
9 | A0A2R8PV67 (/IEP) A0A2R8S019 (/IEP) A2BDW2 (/IEP) A2BDW3 (/IEP) B3DJP3 (/IEP) E9QHI1 (/IEP) F1QYE2 (/IEP) Q4FAI8 (/IEP) Q90484 (/IEP) |
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Axonal fasciculation GO:0007413
The collection of axons into a bundle of rods, known as a fascicle.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
9 | A0A2R8PV67 (/IEP) A0A2R8S019 (/IEP) A2BDW2 (/IEP) A2BDW3 (/IEP) B3DJP3 (/IEP) E9QHI1 (/IEP) F1QYE2 (/IEP) Q4FAI8 (/IEP) Q90484 (/IEP) |
Axon regeneration at neuromuscular junction GO:0014814
The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Optic nerve development GO:0021554
The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Negative regulation of axon extension GO:0030517
Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Positive regulation of synaptic growth at neuromuscular junction GO:0045887
Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Positive regulation of axon regeneration GO:0048680
Any process that activates, maintains or increases the rate of axon regeneration.
|
9 | A0A2R8PV67 (/IMP) A0A2R8S019 (/IMP) A2BDW2 (/IMP) A2BDW3 (/IMP) B3DJP3 (/IMP) E9QHI1 (/IMP) F1QYE2 (/IMP) Q4FAI8 (/IMP) Q90484 (/IMP) |
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
|
2 | A0A0G2K1L0 (/IDA) B2LYI9 (/IDA) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
2 | A0A0G2K1L0 (/IMP) B2LYI9 (/IMP) |
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Odontogenesis of dentin-containing tooth GO:0042475
The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Bud outgrowth involved in lung branching GO:0060447
The process in which a region of the lung epithelium initiates an outgrowth.
|
2 | A0A0G2K1L0 (/IMP) B2LYI9 (/IMP) |
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Cellular response to vitamin D GO:0071305
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Response to fibroblast growth factor GO:0071774
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Cellular response to prostaglandin D stimulus GO:0071799
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.
|
2 | A0A0G2K1L0 (/IEP) B2LYI9 (/IEP) |
Osteoblast differentiation GO:0001649
The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
|
1 | P24821 (/HDA) |
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
|
1 | P24821 (/TAS) |
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
|
1 | Q80YX1 (/ISO) |
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
|
1 | Q80YX1 (/IMP) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
1 | Q80YX1 (/IDA) |
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
1 | P24821 (/IEP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q80YX1 (/IDA) |
Peripheral nervous system axon regeneration GO:0014012
The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.
|
1 | Q80YX1 (/IMP) |
Extracellular matrix organization GO:0030198
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
|
1 | P24821 (/TAS) |
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
1 | Q80YX1 (/ISO) |
Post-translational protein modification GO:0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
|
1 | P24821 (/TAS) |
Cellular protein metabolic process GO:0044267
The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
|
1 | P24821 (/TAS) |
Bud outgrowth involved in lung branching GO:0060447
The process in which a region of the lung epithelium initiates an outgrowth.
|
1 | Q80YX1 (/ISO) |
Mesenchymal-epithelial cell signaling involved in prostate gland development GO:0060739
Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.
|
1 | Q80YX1 (/IMP) |
Prostate gland epithelium morphogenesis GO:0060740
The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
|
1 | Q80YX1 (/IMP) |
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P24821 (/TAS) Q80YX1 (/TAS) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P24821 (/HDA) Q80YX1 (/HDA) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
|
2 | A0A0G2K1L0 (/IDA) B2LYI9 (/IDA) |
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
|
2 | P24821 (/HDA) Q80YX1 (/HDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P24821 (/HDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | Q80YX1 (/IDA) |
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
|
1 | Q80YX1 (/IDA) |
Interstitial matrix GO:0005614
A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
|
1 | Q80YX1 (/IDA) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
1 | H0YYH3 (/IDA) |
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
1 | P24821 (/TAS) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | P24821 (/HDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | P24821 (/HDA) |
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
|
1 | Q80YX1 (/ISO) |
Perisynaptic extracellular matrix GO:0098966
The portion of the extracellular matrix that lies within the perisynaptic space.
|
1 | Q80YX1 (/EXP) |
Perisynaptic extracellular matrix GO:0098966
The portion of the extracellular matrix that lies within the perisynaptic space.
|
1 | Q80YX1 (/IDA) |