The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ctag/Cox11
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: COX11 cytochrome c oxidase assembly homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
10 P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
5 Q2GFE3 (/ISS) Q2GIV9 (/ISS) Q2GIV9 (/ISS) Q2GIV9 (/ISS) Q2GIV9 (/ISS)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q86ZU7 (/ISO) Q9UTM2 (/ISO)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
2 Q54HM6 (/ISS) Q9VMQ6 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q6P8I6 (/IPI) Q9Y6N1 (/IPI)
Methyltransferase activity GO:0008168
Catalysis of the transfer of a methyl group to an acceptor molecule.
2 Q86ZU7 (/ISM) Q9UTM2 (/ISM)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
2 Q8GWR0 (/IDA) Q8GWR0 (/IDA)
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
1 Q9Y6N1 (/TAS)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Respiratory chain complex IV assembly GO:0008535
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
22 Q2GFE3 (/ISS) Q2GIV9 (/ISS) Q2GIV9 (/ISS) Q2GIV9 (/ISS) Q2GIV9 (/ISS) Q5LNX9 (/ISS) Q60AH1 (/ISS) Q8E8Q3 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS)
(12 more)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
10 P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP)
Cellular protein-containing complex assembly GO:0034622
The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
10 P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP) P19516 (/IMP)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
4 Q38BT4 (/ISA) Q38BT4 (/ISA) Q38BT4 (/ISA) Q38BT4 (/ISA)
Aerobic respiration GO:0009060
The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
2 Q54HM6 (/ISS) Q9VMQ6 (/ISS)
Pollen germination GO:0009846
The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
2 Q8GWR0 (/IMP) Q8GWR0 (/IMP)
Post-embryonic root morphogenesis GO:0010101
The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.
2 Q8GWR0 (/IMP) Q8GWR0 (/IMP)
Mitochondrial respiratory chain complex IV assembly GO:0033617
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
2 Q86ZU7 (/ISO) Q9UTM2 (/ISO)
Positive regulation of cytochrome-c oxidase activity GO:1904960
Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
2 Q8GWR0 (/IMP) Q8GWR0 (/IMP)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
1 Q86ZU7 (/NAS)
Mitochondrial translation GO:0032543
The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
1 Q9UTM2 (/TAS)
Negative regulation of glucokinase activity GO:0033132
Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
1 Q6P8I6 (/IDA)
Metal ion homeostasis GO:0055065
Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
1 Q9Y6N1 (/IDA)
Metal ion homeostasis GO:0055065
Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
1 Q6P8I6 (/ISO)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 Q54HM6 (/ISS)

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
14 Q54HM6 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS) Q8IK85 (/ISS)
(4 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
12 P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA) P19516 (/HDA)
(2 more)
Mitochondrial envelope GO:0005740
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
10 P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
10 P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
10 P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA)
Mitochondrial ribosome GO:0005761
A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
10 P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA) P19516 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
7 Q38BT4 (/IDA) Q38BT4 (/IDA) Q38BT4 (/IDA) Q38BT4 (/IDA) Q6P8I6 (/IDA) Q8GWR0 (/IDA) Q8GWR0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q38BT4 (/IDA) Q38BT4 (/IDA) Q38BT4 (/IDA) Q38BT4 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 Q38BT4 (/RCA) Q38BT4 (/RCA) Q38BT4 (/RCA) Q38BT4 (/RCA)
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 A3KMZ6 (/ISS) Q5R7U6 (/ISS) Q6P8I6 (/ISS)
Mitochondrial small ribosomal subunit GO:0005763
The smaller of the two subunits of a mitochondrial ribosome.
2 Q86ZU7 (/ISO) Q9UTM2 (/ISO)
Integral component of mitochondrial membrane GO:0032592
The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q8GWR0 (/IDA) Q8GWR0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 E9ACF7 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9Y6N1 (/TAS)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
1 Q9UTM2 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q59PA0 (/IDA)
Intrinsic component of mitochondrial inner membrane GO:0031304
The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 Q9UTM2 (/IDA)
Intrinsic component of mitochondrial inner membrane GO:0031304
The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1 Q86ZU7 (/ISS)
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9Y6N1 (/IDA)
Integral component of mitochondrial inner membrane GO:0031305
The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6P8I6 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9Y6N1 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q6P8I6 (/ISO)
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