CATH Superfamily 2.60.120.970
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 38: Transforming growth factor beta-2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Type II transforming growth factor beta receptor binding GO:0005114
Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Type III transforming growth factor beta receptor binding GO:0034714
Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Amyloid-beta binding GO:0001540
Interacting selectively and non-covalently with amyloid-beta peptide/protein and/or its precursor.
|
4 | F6ZJW6 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
4 | F6ZJW6 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
|
4 | F6ZJW6 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
4 | F6ZJW6 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Type I transforming growth factor beta receptor binding GO:0034713
Interacting selectively and non-covalently with a type I transforming growth factor beta receptor.
|
1 | K4P236 (/ISS) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | K4P236 (/ISS) |
|
Transforming growth factor beta binding GO:0050431
Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
|
1 | K4P236 (/ISS) |
Showing 1 to 9 of 9 entries
There are 54 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transforming growth factor beta receptor signaling pathway GO:0007179
A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Salivary gland morphogenesis GO:0007435
The process in which the anatomical structures of the salivary gland are generated and organized.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Positive regulation of epithelial to mesenchymal transition GO:0010718
Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Negative regulation of macrophage cytokine production GO:0010936
Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Cell-cell junction organization GO:0045216
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
|
4 | F6ZJW6 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
4 | F6ZJW6 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
Showing 1 to 10 of 54 entries
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
|
5 | F6ZJW6 (/ISS) K4P236 (/ISS) Q8CDZ9 (/ISS) Q921T1 (/ISS) R0L9V9 (/ISS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | F6ZJW6 (/ISS) R0L9V9 (/ISS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | F6ZJW6 (/ISS) R0L9V9 (/ISS) |
Showing 1 to 3 of 3 entries
