The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
B-lactam Antibiotic, Isopenicillin N Synthase; Chain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
2
172
3D
1wa6X00 - 76.1
1
162 - - 90.2
4
157
3D
5apaA00 - 62.2
3
148 - - 89.6
5
143 - - 92.7
6
II
103 - - 92.8
7
100 - - 92.2
9
85
3D
2brtA00 - 89.1
8
82 - - 76.4
10
74 - - 88.1
11
73 - - 52.6
12
69 - - 94.3
13
66 - - 90.9
14
63 - - 89.4
15
61 - - 93.5
16
61 - - 84.3
17
58 - - 95.1
18
2OG II
53 - - 93.9
20
52 - - 2.5
19
52 - - 73.8
21
52 - - 83.7
22
52 - - 95.0
23
49
3D
4xaeB00 - 89.3
30
43
3D
5c3sD00 - 87.7
163
41
3D
4bb3A00 - 0.0
24
38 - - 75.3
25
37 - - 89.3
26
32 - - 90.0
27
31 - - 78.1
29
27 - - 63.9
28
27 - - 47.9
31
2OG II
26 - - 71.0
32
25 - - 72.9
33
24 - - 72.0
35
22 - - 58.5
36
II
22 - - 78.2
34
2OG II
22 - - 71.3
37
21 - - 71.7
39
20 - - 75.9
38
20 - - 95.2
40
18 - - 90.3
41
17 - - 76.8
42
17 - - 82.6
43
16 - - 33.3
45
II
15 - - 83.8
44
2OG II
15 - - 76.5
46
13 - - 55.4
47
13 - - 88.7
51
12 - - 86.8
48
II
12 - - 32.9
49
12 - - 77.4
50
12 - - 75.7
52
11 - - 65.5
53
11 - - 8.8
55
10 - - 17.2
56
10 - - 11.9
54
10 - - 73.6
58
9 - - 9.7
57
II
9 - - 81.9
61
8 - - 79.0
60
8 - - 6.9
59
8 - - 38.5
62
8 - - 58.1
64
7 - - 90.3
63
7 - - 11.5
65
6 - - 12.5
66
6 - - 63.5
67
6 - - 57.2
71
5 - - 75.1
68
5 - - 40.5
69
5 - - 6.2
70
2OG II
5 - - 75.6
78
4 - - 5.0
85
4 - - 57.6
74
4 - - 67.8
80
4 - - 72.2
82
4 - - 45.9
81
4 - - 16.6
75
II
4 - - 12.0
76
4 - - 9.1
84
4 - - 77.4
77
4 - - 6.1
79
4 - - 21.8
72
4 - - 18.8
73
4 - - 49.6
83
4 - - 64.0
96
3 - - 32.5
89
3 - - 6.0
91
Ii
3 - - 3.6
92
3 - - 7.7
94
II
3 - - 4.4
90
3 - - 6.0
95
3 - - 11.3
86
3 - - 20.5
87
3 - - 36.8
93
II
3 - - 4.4
97
3 - - 32.7
88
3 - - 34.4
127
2 - - 0.0
153
2 - - 38.7
101
2 - - 9.1
136
2 - - 39.1
116
II
2 - - 0.0
137
2 - - 19.5
112
2 - - 2.8
108
2 - - 3.3
142
2 - - 0.0
128
2 - - 3.0
155
2 - - 45.5
154
2 - - 42.0
158
2 - - 33.0
132
2 - - 0.0
147
2 - - 43.4
117
II
2 - - 3.6
149
2OG II
2 - - 34.8
105
2 - - 38.6
111
2 - - 6.0
139
2 - - 0.0
129
2 - - 4.8
135
2 - - 42.0
145
2 - - 3.9
124
2 - - 0.0
113
2OG II
2 - - 0.0
152
II
2 - - 36.6
120
2 - - 0.0
109
2 - - 5.5
99
2 - - 27.3
131
2 - - 8.6
148
2 - - 18.2
106
2 - - 2.6
157
2 - - 21.8
121
2 - - 0.0
141
2 - - 0.0
146
2 - - 21.8
98
2 - - 24.3
119
2 - - 0.0
107
2 - - 1.9
144
2OG II
2 - - 0.0
151
2 - - 37.6
138
2 - - 9.8
110
2 - - 0.3
130
2 - - 0.0
102
2 - - 33.4
140
II AFU_orthologue AFUA_5G12242
2 - - 0.7
115
2 - - 0.4
122
2 - - 0.0
125
2 - - 2.6
156
2 - - 43.5
118
2 - - 0.0
100
2 - - 23.0
126
II
2 - - 0.0
150
2 - - 37.8
114
2 - - 4.3
104
2 - - 34.3
103
2 - - 34.9
143
2 - - 10.5
133
2 - - 31.1
123
2 - - 0.0
134
2 - - 0.0
180
1 - - 0.0
191
1 - - 0.0
187
1 - - 0.0
212
1 - - 0.0
170
1 - - 0.0
232
1 - - 0.0
225
1 - - 0.0
207
1 - - 0.0
175
1 - - 0.0
198
1 - - 0.0
202
1 - - 0.0
184
1 - - 0.0
181
1 - - 0.0
229
1 - - 0.0
222
1 - - 0.0
217
1 - - 0.0
165
1 - - 0.0
209
1 - - 0.0
210
1 - - 0.0
242
1 - - 0.0
168
1 - - 0.0
178
1 - - 0.0
213
1 - - 0.0
200
1 - - 0.0
161
1 - - 0.0
224
1 - - 0.0
192
1 - - 0.0
233
1 - - 0.0
199
1 - - 0.0
195
1 - - 0.0
174
1 - - 0.0
188
1 - - 0.0
183
1 - - 0.0
203
1 - - 0.0
204
1 - - 0.0
228
II AFU_orthologue AFUA_5G12242
1 - - 0.0
238
1 - - 0.0
179
1 - - 0.0
164
1 - - 0.0
211
1 - - 0.0
236
1 - - 0.0
218
1 - - 0.0
234
1 - - 0.0
160
1 - - 0.0
193
1 - - 0.0
189
1 - - 0.0
221
1 - - 0.0
177
1 - - 0.0
205
1 - - 0.0
227
1 - - 0.0
182
1 - - 0.0
167
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
214
1 - - 0.0
239
1 - - 0.0
186
2OG II
1 - - 0.0
173
1 - - 0.0
219
1 - - 0.0
196
1 - - 0.0
206
1 - - 0.0
194
1 - - 0.0
220
1 - - 0.0
226
1 - - 0.0
237
1 - - 0.0
235
2OG II
1 - - 0.0
171
1 - - 0.0
197
1 - - 0.0
176
1 - - 0.0
215
1 - - 0.0
208
1 - - 0.0
241
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
201
1 - - 0.0
169
2OG II
1 - - 0.0
190
1 - - 0.0
231
1 - - 0.0
172
1 - - 0.0
223
1 - - 0.0
216
1 - - 0.0
166
1 - - 0.0
185
1 - - 0.0
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