The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 89: growth arrest-specific protein 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 26 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Protein tyrosine kinase activator activity GO:0030296
Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0043027
Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Receptor ligand activity GO:0048018
The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).
2 Q14393 (/IDA) Q61592 (/IDA)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
1 Q14393 (/IDA)
Phosphatidylserine binding GO:0001786
Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
1 Q61592 (/ISO)
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
1 Q14393 (/IDA)
Showing 1 to 10 of 26 entries

There are 174 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q14393 (/ISS) Q61592 (/ISS)
Positive regulation of cytokine-mediated signaling pathway GO:0001961
Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Positive regulation of glomerular filtration GO:0003104
Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q14393 (/ISS) Q61592 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Phagocytosis GO:0006909
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Negative regulation of tumor necrosis factor-mediated signaling pathway GO:0010804
Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Peptidyl-serine phosphorylation GO:0018105
The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Showing 1 to 10 of 174 entries

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS) Q61592 (/ISS) Q63772 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
8 F1MZ40 (/ISS) F6SWZ6 (/ISS) G1LCY3 (/ISS) G1P9P1 (/ISS) G3I7Z5 (/ISS) G3TKE9 (/ISS) H0V9V5 (/ISS) H0XUI2 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
3 Q14393 (/IDA) Q61592 (/IDA) Q63772 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q14393 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q61592 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q61592 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q14393 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q61592 (/ISO)
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
1 Q14393 (/TAS)
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
1 Q14393 (/TAS)
Showing 1 to 10 of 12 entries
CATH-Gene3D is a Global Biodata Core Resource Learn more...