The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Jelly Rolls
".
FunFam 12: neuropathy target esterase isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
|
2 | A2AJ88 (/EXP) Q8IY17 (/EXP) |
Carboxylic ester hydrolase activity GO:0052689
Catalysis of the hydrolysis of a carboxylic ester bond.
|
2 | F1R844 (/ISS) Q3TRM4 (/ISS) |
Lysophospholipase activity GO:0004622
Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
|
1 | Q3TRM4 (/ISO) |
Carboxylic ester hydrolase activity GO:0052689
Catalysis of the hydrolysis of a carboxylic ester bond.
|
1 | Q5BK26 (/IMP) |
Carboxylic ester hydrolase activity GO:0052689
Catalysis of the hydrolysis of a carboxylic ester bond.
|
1 | A2AJ88 (/ISO) |
There are 12 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Membrane lipid metabolic process GO:0006643
The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Glial cell apoptotic process GO:0034349
Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Phosphatidylcholine metabolic process GO:0046470
The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Neuron apoptotic process GO:0051402
Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | Q3TRM4 (/IMP) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
1 | F1R844 (/IMP) |
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
1 | Q3TRM4 (/IMP) |
Anterior/posterior axis specification GO:0009948
The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | F1R844 (/IMP) |
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | F1R844 (/IMP) |
Glycerophospholipid catabolic process GO:0046475
The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
|
1 | Q8IY17 (/TAS) |
Neuron development GO:0048666
The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
|
1 | F1R844 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
10 | B3MRI9 (/ISS) B3NY03 (/ISS) B4H3U8 (/ISS) B4IL64 (/ISS) B4JLX2 (/ISS) B4L535 (/ISS) B4M709 (/ISS) B4N1W9 (/ISS) B4Q0P3 (/ISS) B5DKS8 (/ISS) |
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
|
2 | A2AJ88 (/TAS) Q8IY17 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q8IY17 (/HDA) |