The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Acid Proteases
".
FunFam 24: Endothiapepsin
There are 2 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
| EC Term | Annotations | Evidence |
|---|---|---|
|
Aspergillopepsin I.
[EC: 3.4.23.18]
Hydrolysis of proteins with broad specificity. Generally favors hydrophobic residues in P1 and P1', but also accepts Lys in P1, which leads to activation of trypsinogen. Does not clot milk.
|
64 |
A0A0J5Q5Z0
A0A0J5Q5Z0
A0A0J5Q5Z0
A0A0J5Q5Z0
A0A100IK58
A0A100IK58
A0A1S9D891
A0A1S9D891
A0A1S9D891
A0A1S9D891 (54 more...) |
|
Penicillopepsin.
[EC: 3.4.23.20]
Hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving 20-Gly-|-Glu-21 in the B chain of insulin. Clots milk, and activates trypsinogen.
|
2 | P78735 Q01972 |
