The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Nucleic acid-binding proteins
".
FunFam 94: cold shock domain-containing protein E1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O75534 (/IPI) O75534 (/IPI) O75534 (/IPI) O75534 (/IPI) Q960S8 (/IPI) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
4 | O75534 (/HDA) O75534 (/HDA) O75534 (/HDA) O75534 (/HDA) |
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
|
1 | Q960S8 (/IPI) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
4 | O75534 (/TAS) O75534 (/TAS) O75534 (/TAS) O75534 (/TAS) |
Nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
|
4 | O75534 (/IMP) O75534 (/IMP) O75534 (/IMP) O75534 (/IMP) |
Nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
|
2 | Q91W50 (/ISO) Q91W50 (/ISO) |
Dosage compensation GO:0007549
Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.
|
1 | Q960S8 (/IDA) |
Dosage compensation by hyperactivation of X chromosome GO:0009047
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.
|
1 | Q960S8 (/IDA) |
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
1 | Q960S8 (/IDA) |
Dosage compensation complex assembly GO:0042714
The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.
|
1 | Q960S8 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
17 |
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
(7 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
17 |
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
(7 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
17 |
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0E2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
A0A024R0K2 (/IDA)
(7 more) |
CRD-mediated mRNA stability complex GO:0070937
A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.
|
4 | O75534 (/IDA) O75534 (/IDA) O75534 (/IDA) O75534 (/IDA) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | Q91W50 (/HDA) Q91W50 (/HDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
2 | Q91W50 (/ISO) Q91W50 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q91W50 (/ISO) Q91W50 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q91W50 (/ISO) Q91W50 (/ISO) |
CRD-mediated mRNA stability complex GO:0070937
A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.
|
2 | Q91W50 (/ISO) Q91W50 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q960S8 (/IDA) |