The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Netrin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 A0A0B5JPZ7 (/IPI) B0CM04 (/IPI) O09118 (/IPI) O95631 (/IPI) O95631 (/IPI) O95631 (/IPI) O95631 (/IPI) Q90922 (/IPI)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
1 O09118 (/RCA)
Showing 1 to 2 of 2 entries

There are 57 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Substrate-dependent cell migration, cell extension GO:0006930
The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell.
7 O09118 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) Q2HXW4 (/ISS) Q90922 (/ISS)
Ras protein signal transduction GO:0007265
A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
7 O09118 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) Q2HXW4 (/ISS) Q90922 (/ISS)
Cdc42 protein signal transduction GO:0032488
A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.
7 O09118 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) Q2HXW4 (/ISS) Q90922 (/ISS)
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
7 O09118 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) Q2HXW4 (/ISS) Q90922 (/ISS)
Dendrite development GO:0016358
The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.
6 A0A0B5JPZ7 (/IGI) B0CM04 (/IGI) B3DJ84 (/IGI) F1QUK5 (/IGI) O42140 (/IGI) O42203 (/IGI)
Central nervous system projection neuron axonogenesis GO:0021952
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
6 A0A0B5JPZ7 (/IGI) B0CM04 (/IGI) B3DJ84 (/IGI) F1QUK5 (/IGI) O42140 (/IGI) O42203 (/IGI)
Anterior commissure morphogenesis GO:0021960
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.
6 A0A0B5JPZ7 (/IGI) B0CM04 (/IGI) B3DJ84 (/IGI) F1QUK5 (/IGI) O42140 (/IGI) O42203 (/IGI)
Anterior commissure morphogenesis GO:0021960
Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.
6 A0A0B5JPZ7 (/IMP) B0CM04 (/IMP) B3DJ84 (/IMP) F1QUK5 (/IMP) O42140 (/IMP) O42203 (/IMP)
Regulation of axon extension GO:0030516
Any process that modulates the rate, direction or extent of axon extension.
6 A0A0B5JPZ7 (/IGI) B0CM04 (/IGI) B3DJ84 (/IGI) F1QUK5 (/IGI) O42140 (/IGI) O42203 (/IGI)
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
6 O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) O95631 (/ISS) Q2HXW4 (/ISS) Q90922 (/ISS)
Showing 1 to 10 of 57 entries

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
6 O09118 (/TAS) O95631 (/TAS) O95631 (/TAS) O95631 (/TAS) O95631 (/TAS) Q924Z9 (/TAS)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
1 O09118 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O09118 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 Q924Z9 (/IDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 O09118 (/ISO)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 O09118 (/HDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
1 Q90922 (/IDA)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
1 O09118 (/ISO)
Showing 1 to 8 of 8 entries
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