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CATH Superfamily 2.40.420.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Cation efflux system protein cusB

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion transmembrane transporter activity GO:0005375
Enables the transfer of copper (Cu) ions from one side of a membrane to the other.
 24 P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI)
(14 more)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
 24 P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA)
(14 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 24 P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI) P77239 (/IPI)
(14 more)
Transition metal ion binding GO:0046914
Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
 24 P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA)
(14 more)
Metal ion transmembrane transporter activity GO:0046873
Enables the transfer of metal ions from one side of a membrane to the other.
 3 Q605L7 (/ISS) Q8E807 (/ISS) Q8E8R4 (/ISS)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
 24 P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI)
(14 more)
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
 24 P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP)
(14 more)
Response to silver ion GO:0010272
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
 24 P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP)
(14 more)
Response to silver ion GO:0010272
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
 24 P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP)
(14 more)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
 24 P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI)
(14 more)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
 24 P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP)
(14 more)
Plasma membrane copper ion transport GO:0015679
The directed movement of copper ions across the plasma membrane.
 24 P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI)
(14 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 24 P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP) P77239 (/IEP)
(14 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 24 P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP) P77239 (/IMP)
(14 more)
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
 24 P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI) P77239 (/IGI)
(14 more)
Metal ion transport GO:0030001
The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 3 Q605L7 (/ISS) Q8E807 (/ISS) Q8E8R4 (/ISS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Outer membrane-bounded periplasmic space GO:0030288
The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
 24 P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA) P77239 (/IDA)
(14 more)
Cell outer membrane GO:0009279
A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
 1 Q0BZM6 (/ISS)
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