The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Lyase, Ornithine Decarboxylase; Chain A, domain 1
".
FunFam 5: Ornithine decarboxylase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 9 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Ornithine decarboxylase activity GO:0004586
Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
|
6 | P00860 (/IDA) P07805 (/IDA) P07805 (/IDA) P09057 (/IDA) P11926 (/IDA) P27119 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
6 | P09057 (/ISS) P11926 (/ISS) P14019 (/ISS) P27117 (/ISS) P27117 (/ISS) P27119 (/ISS) |
Ornithine decarboxylase activity GO:0004586
Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
|
5 | P11926 (/ISS) P14019 (/ISS) P27117 (/ISS) P27117 (/ISS) P27119 (/ISS) |
Ornithine decarboxylase activity GO:0004586
Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
|
2 | P00860 (/ISO) P27119 (/ISO) |
Ornithine decarboxylase activity GO:0004586
Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
|
1 | P11926 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P11926 (/IPI) |
Putrescine transmembrane transporter activity GO:0015489
Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
|
1 | Q9I8S4 (/ISS) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P00860 (/IDA) |
Ornithine decarboxylase activator activity GO:0042978
Upregulation of the activity of the enzyme ornithine decarboxylase.
|
1 | Q9I8S4 (/ISS) |
Showing 1 to 9 of 9 entries
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Putrescine biosynthetic process from ornithine GO:0033387
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.
|
6 | P09057 (/ISS) P11926 (/ISS) P14019 (/ISS) P27117 (/ISS) P27117 (/ISS) P27119 (/ISS) |
Regulation of protein catabolic process GO:0042176
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
6 | P09057 (/ISS) P11926 (/ISS) P14019 (/ISS) P27117 (/ISS) P27117 (/ISS) P27119 (/ISS) |
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
|
2 | P00860 (/IMP) P27119 (/IMP) |
Polyamine metabolic process GO:0006595
The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
|
2 | P00860 (/ISO) P27119 (/ISO) |
Polyamine biosynthetic process GO:0006596
The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
|
2 | P07805 (/TAS) P07805 (/TAS) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P00860 (/IMP) P27119 (/IMP) |
Putrescine biosynthetic process GO:0009446
The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.
|
2 | P00860 (/ISO) P27119 (/ISO) |
Regulation of cellular amino acid metabolic process GO:0006521
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.
|
1 | P11926 (/TAS) |
Polyamine metabolic process GO:0006595
The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
|
1 | P09057 (/IDA) |
Polyamine metabolic process GO:0006595
The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
|
1 | P11926 (/TAS) |
Showing 1 to 10 of 20 entries
There are 18 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P11926 (/ISS) P14019 (/ISS) P27117 (/ISS) P27117 (/ISS) P27118 (/ISS) P27119 (/ISS) P27120 (/ISS) Q9I8S4 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P00860 (/IDA) P09057 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P00860 (/ISO) P27119 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P00860 (/IDA) P27119 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
2 | P00860 (/ISO) P27119 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9I8S4 (/ISS) |
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
|
1 | Q9I8S4 (/ISS) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
1 | Q9I8S4 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P11926 (/TAS) |
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
|
1 | Q9I8S4 (/ISS) |
Showing 1 to 10 of 18 entries