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CATH Superfamily 2.40.37.10

Lyase, Ornithine Decarboxylase; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Lyase, Ornithine Decarboxylase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13: Carboxynorspermidine decarboxylase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Carboxynorspermidine decarboxylase. [EC: 4.1.1.96]
(1) Carboxynorspermidine = bis(3-aminopropyl)amine + CO(2). (2) Carboxyspermidine = spermidine + CO(2).
  • Part of a bacterial polyamine biosynthesis pathway.
  • The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae.
  • The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro.
 4 A0A1J6UGJ2 A0A1J6UGJ2 A8FNH9 A8FNH9
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