The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 4: Retinol-binding protein 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
|
12 |
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P04916 (/IDA)
P04916 (/IDA)
P18902 (/IDA)
P27485 (/IDA)
(2 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | P02753 (/IPI) P02753 (/IPI) P02753 (/IPI) P02753 (/IPI) P02753 (/IPI) P02753 (/IPI) P41263 (/IPI) Q00724 (/IPI) |
Retinol transmembrane transporter activity GO:0034632
Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.
|
7 | P02753 (/IC) P02753 (/IC) P02753 (/IC) P02753 (/IC) P02753 (/IC) P02753 (/IC) P41263 (/IC) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | P04916 (/IDA) P04916 (/IDA) |
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | P41263 (/IDA) |
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
|
1 | P41263 (/IPI) |
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
|
1 | P41263 (/ISM) |
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
|
1 | Q00724 (/ISO) |
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
|
1 | M5AXY1 (/ISS) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | P41263 (/IPI) |
Showing 1 to 10 of 11 entries
There are 70 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
8 | A0A0R4IVC3 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) Q9PT95 (/IDA) |
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
7 | P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) Q00724 (/IMP) |
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
7 | P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) Q00724 (/IMP) |
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
|
6 | P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) |
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
6 | P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) |
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
6 | P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
6 | P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) |
Maintenance of gastrointestinal epithelium GO:0030277
Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.
|
6 | P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) P02753 (/IDA) |
Lung development GO:0030324
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
|
6 | P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) P02753 (/ISS) |
Positive regulation of insulin secretion GO:0032024
Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
|
6 | P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) P02753 (/IMP) |
Showing 1 to 10 of 70 entries
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
20 |
M5AXY1 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P02753 (/IDA)
P04916 (/IDA)
P04916 (/IDA)
P06912 (/IDA)
(10 more) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
14 |
P02753 (/ISS)
P02753 (/ISS)
P02753 (/ISS)
P02753 (/ISS)
P02753 (/ISS)
P02753 (/ISS)
P06172 (/ISS)
P61641 (/ISS)
P61641 (/ISS)
P61641 (/ISS)
(4 more) |
Yolk GO:0060417
The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.
|
7 | P24774 (/IDA) P24775 (/IDA) P41263 (/IDA) Q71B03 (/IDA) Q8JIZ4 (/IDA) Q90Y51 (/IDA) Q90Y51 (/IDA) |
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
6 | P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) P02753 (/TAS) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
6 | P02753 (/HDA) P02753 (/HDA) P02753 (/HDA) P02753 (/HDA) P02753 (/HDA) P02753 (/HDA) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
2 | P04916 (/IDA) P04916 (/IDA) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P41263 (/ISM) |
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | Q00724 (/ISO) |
Clathrin-coated vesicle GO:0030136
A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
|
1 | P41263 (/IDA) |
Showing 1 to 10 of 13 entries