The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

The modification of a protein by cis-trans isomerization of a proline residue.

The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.

The modification of a protein by cis-trans isomerization of a proline residue.

The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.

Any process that activates or increases the frequency, rate or extent of viral genome replication.

The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.

The modification of a protein by cis-trans isomerization of a proline residue.

Any process that activates or increases the frequency, rate or extent of viral genome replication.

That part of the nuclear content other than the chromosomes or the nucleolus.

Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.

A ribonucleoprotein complex that contains base-paired U4 and U6 small nuclear RNAs.

A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.

A ribonucleoprotein complex that contains base-paired U4 and U6 small nuclear RNAs.