The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Trypsin-like serine proteases
".
FunFam 344: Plasminogen activator, urokinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P06869 (/IPI) P06869 (/IPI) |
|
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
|
2 | P06869 (/ISO) P06869 (/ISO) |
Showing 1 to 2 of 2 entries
There are 19 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | P06869 (/IMP) P06869 (/IMP) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Regulation of signaling receptor activity GO:0010469
Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Smooth muscle cell migration GO:0014909
The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.
|
2 | P06869 (/IMP) P06869 (/IMP) |
|
Regulation of smooth muscle cell migration GO:0014910
Any process that modulates the frequency, rate or extent of smooth muscle cell migration.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Positive regulation of smooth muscle cell migration GO:0014911
Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Plasminogen activation GO:0031639
The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Regulation of cell adhesion mediated by integrin GO:0033628
Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
|
2 | P06869 (/ISO) P06869 (/ISO) |
Showing 1 to 10 of 19 entries
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | P06869 (/ISO) P06869 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | P06869 (/ISO) P06869 (/ISO) |
Showing 1 to 3 of 3 entries
