The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Leishmanolysin domain 4
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Major surface protease gp63, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
6 Q384F7 (/ISM) Q384P2 (/ISM) Q384P3 (/ISM) Q580F9 (/ISM) Q580G0 (/ISM) Q580G2 (/ISM)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q384P2 (/ISM)
Showing 1 to 2 of 2 entries

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
6 Q384F7 (/ISM) Q384P2 (/ISM) Q384P3 (/ISM) Q580F9 (/ISM) Q580G0 (/ISM) Q580G2 (/ISM)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
6 Q384F7 (/ISM) Q384P2 (/ISM) Q384P3 (/ISM) Q580F9 (/ISM) Q580G0 (/ISM) Q580G2 (/ISM)
Showing 1 to 2 of 2 entries

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
6 Q384F7 (/ISM) Q384P2 (/ISM) Q384P3 (/ISM) Q580F9 (/ISM) Q580G0 (/ISM) Q580G2 (/ISM)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q384F7 (/IDA)
Nuclear lumen GO:0031981
The volume enclosed by the nuclear inner membrane.
1 Q384F7 (/IDA)
Ciliary plasm GO:0097014
All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
1 Q384F7 (/IDA)
Showing 1 to 4 of 4 entries
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