View in Gene3D

CATH Superfamily 2.30.30.60

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: MscS Mechanosensitive ion channel

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
 113 P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI) P0C0S1 (/IPI)
(103 more)
Mechanosensitive ion channel activity GO:0008381
Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress.
 111 P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA)
(101 more)
Transporter activity GO:0005215
Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
 1 Q8EJ80 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 1 P73148 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular water homeostasis GO:0009992
Any process involved in the maintenance of an internal steady state of water within a cell.
 132 P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP) P0C0S1 (/IMP)
(122 more)
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
 111 P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA)
(101 more)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
 111 P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA)
(101 more)
Regulation of nitrogen compound metabolic process GO:0051171
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
 1 P73148 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 111 P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA)
(101 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 111 P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA) P0C0S1 (/IDA)
(101 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 55 P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA) P75783 (/IDA)
(45 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 34 P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA) P75783 (/RCA)
(24 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...