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CATH Superfamily 2.30.30.490

Bromo adjacent homology (BAH) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Bromo adjacent homology (BAH) domain

This entry represents the BAH (bromo-adjacent homology) domain which is commonly found in chromatin-associated proteins PMID:23907388. The BAH domain appears to act as a protein-protein interaction module specialised in gene silencing, as suggested for example by its interaction within yeast Orc1p with the silent information regulator Sir1p. The BAH module might therefore play an important role by linking DNA methylation, replication and transcriptional regulation PMID:10100640.

PMID:23907388 PMID:10100640

GO Diversity

Unique GO annotations
305 Unique GO terms

EC Diversity

Unique EC annotations
3 Unique EC terms

Species Diversity

Unique species annotations
1499 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 44
Domain clusters (>95% seq id): 11
Domain clusters (>35% seq id): 9
Unique PDBs: 23
Alignments
Structural Clusters (5A): 4
Structural Clusters (9A): 3
FunFam Clusters: 103
Function
Unique EC: 3
Unique GO: 305
Taxonomy
Unique Species: 1499
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