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CATH Superfamily 2.30.30.30

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: 60S ribosomal protein L8

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 63 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(53 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 59 P46286 (/IPI) P46286 (/IPI) P62918 (/IPI) P62918 (/IPI) P62918 (/IPI) P62918 (/IPI) P62918 (/IPI) P62918 (/IPI) P62918 (/IPI) P62918 (/IPI)
(49 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 57 P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA)
(47 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 57 P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS)
(47 more)
5.8S rRNA binding GO:1990932
Interacting selectively and non-covalently with 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.
 57 P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA) P62919 (/IDA)
(47 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 38 P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX46 (/IDA) P0CX46 (/IDA)
(28 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 9 P0CT70 (/ISO) P0CT70 (/ISO) P0CT70 (/ISO) P0CT71 (/ISO) P0CT71 (/ISO) P0CT71 (/ISO) P0CT72 (/ISO) P0CT72 (/ISO) P0CT72 (/ISO)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
 9 P0CT70 (/ISM) P0CT70 (/ISM) P0CT70 (/ISM) P0CT71 (/ISM) P0CT71 (/ISM) P0CT71 (/ISM) P0CT72 (/ISM) P0CT72 (/ISM) P0CT72 (/ISM)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
 6 Q9V3G1 (/HDA) Q9V3G1 (/HDA) Q9V3G1 (/HDA) Q9V3G1 (/HDA) Q9V3G1 (/HDA) Q9V3G1 (/HDA)
Showing 1 to 10 of 13 entries

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
 73 P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX46 (/IDA) P0CX46 (/IDA)
(63 more)
Cytoplasmic translation GO:0002181
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
 66 P0CT70 (/ISO) P0CT70 (/ISO) P0CT70 (/ISO) P0CT71 (/ISO) P0CT71 (/ISO) P0CT71 (/ISO) P0CT72 (/ISO) P0CT72 (/ISO) P0CT72 (/ISO) P62918 (/ISO)
(56 more)
Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184
The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
 57 P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS) P62917 (/NAS)
(47 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
SRP-dependent cotranslational protein targeting to membrane GO:0006614
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
Viral transcription GO:0019083
The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
 57 P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP) P62919 (/IEP)
(47 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
 16 Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS) Q8I3T9 (/ISS)
(6 more)
Showing 1 to 10 of 14 entries

There are 31 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
 152 P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX45 (/IDA) P0CX46 (/IDA) P0CX46 (/IDA)
(142 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
 66 P0CT70 (/ISO) P0CT70 (/ISO) P0CT70 (/ISO) P0CT71 (/ISO) P0CT71 (/ISO) P0CT71 (/ISO) P0CT72 (/ISO) P0CT72 (/ISO) P0CT72 (/ISO) P62918 (/ISO)
(56 more)
Cytosolic large ribosomal subunit GO:0022625
The large subunit of a ribosome located in the cytosol.
 63 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(53 more)
Polysomal ribosome GO:0042788
A ribosome bound to mRNA that forms part of a polysome.
 63 P46286 (/IDA) P46286 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA)
(53 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 57 P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS) P62917 (/TAS)
(47 more)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
 57 P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA)
(47 more)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
 57 P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP) P62917 (/EXP)
(47 more)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
 57 P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA) P62917 (/IDA)
(47 more)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
 57 P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO) P62918 (/ISO)
(47 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 57 P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA) P62917 (/HDA)
(47 more)
Showing 1 to 10 of 31 entries
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