The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Adenine nucleotide alpha hydrolases-like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: tRNA-specific 2-thiouridylase MnmA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
67 P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA)
(57 more)
TRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity GO:0004808
Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.
4 Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS)
Sulfurtransferase activity GO:0016783
Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
4 Q12093 (/TAS) Q12093 (/TAS) Q12093 (/TAS) Q12093 (/TAS)
TRNA-5-taurinomethyluridine 2-sulfurtransferase GO:0061708
Catalysis of 5-taurinomethyluridine in tRNA + a
4 Q12093 (/IMP) Q12093 (/IMP) Q12093 (/IMP) Q12093 (/IMP)
TRNA-5-taurinomethyluridine 2-sulfurtransferase GO:0061708
Catalysis of 5-taurinomethyluridine in tRNA + a
1 O13947 (/ISO)
TRNA U34 thiol-transferase activity GO:0106054
Catalysis of the reaction: uridine34 in tRNA + a
1 O13947 (/NAS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA wobble position uridine thiolation GO:0002143
The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
67 P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA)
(57 more)
TRNA wobble position uridine thiolation GO:0002143
The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
67 P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP) P25745 (/IMP)
(57 more)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
4 Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS) Q9KSX8 (/ISS)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
4 Q12093 (/TAS) Q12093 (/TAS) Q12093 (/TAS) Q12093 (/TAS)
Mitochondrial tRNA wobble position uridine thiolation GO:1990799
The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
4 Q12093 (/IMP) Q12093 (/IMP) Q12093 (/IMP) Q12093 (/IMP)
Mitochondrial tRNA wobble position uridine thiolation GO:1990799
The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
1 O13947 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
67 P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA) P25745 (/IDA)
(57 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 O13947 (/HDA) Q12093 (/HDA) Q12093 (/HDA) Q12093 (/HDA) Q12093 (/HDA) Q9DAT5 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 O75648 (/IDA) Q12093 (/IDA) Q12093 (/IDA) Q12093 (/IDA) Q12093 (/IDA) Q9DAT5 (/IDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
4 Q12093 (/TAS) Q12093 (/TAS) Q12093 (/TAS) Q12093 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 O75648 (/ISS) Q17440 (/ISS) Q54I63 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O75648 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9DAT5 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9DAT5 (/ISO)
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