The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Ribonuclease P/MRP, subunit p29
".
FunFam 1: Ribonuclease P protein subunit p29
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ribonuclease P RNA binding GO:0033204
Interacting selectively and non-covalently with the RNA subunit of ribonuclease P.
|
5 | Q2KIB9 (/ISS) Q5M882 (/ISS) Q5R7B0 (/ISS) Q5R7B0 (/ISS) Q9CR08 (/ISS) |
|
Ribonuclease P RNA binding GO:0033204
Interacting selectively and non-covalently with the RNA subunit of ribonuclease P.
|
2 | O95707 (/IDA) Q54IT0 (/IDA) |
|
Ribonuclease P activity GO:0004526
Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.
|
1 | Q54IT0 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O95707 (/IPI) |
|
Ribonuclease P RNA binding GO:0033204
Interacting selectively and non-covalently with the RNA subunit of ribonuclease P.
|
1 | Q9CR08 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
TRNA 5'-leader removal GO:0001682
Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
|
5 | Q2KIB9 (/ISS) Q5M882 (/ISS) Q5R7B0 (/ISS) Q5R7B0 (/ISS) Q9CR08 (/ISS) |
|
TRNA 5'-leader removal GO:0001682
Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
|
1 | O95707 (/IDA) |
|
TRNA 5'-leader removal GO:0001682
Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
|
1 | Q9CR08 (/ISO) |
|
TRNA 5'-leader removal GO:0001682
Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
|
1 | O95707 (/TAS) |
|
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
1 | Q54IT0 (/ISS) |
|
TRNA processing GO:0008033
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
|
1 | Q54IT0 (/ISS) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Multimeric ribonuclease P complex GO:0030681
A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.
|
5 | Q2KIB9 (/ISS) Q5M882 (/ISS) Q5R7B0 (/ISS) Q5R7B0 (/ISS) Q9CR08 (/ISS) |
|
Ribonuclease MRP complex GO:0000172
A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
|
1 | Q54IT0 (/ISS) |
|
Ribonuclease MRP complex GO:0000172
A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
|
1 | O95707 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | O95707 (/TAS) |
|
Nucleolar ribonuclease P complex GO:0005655
A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.
|
1 | Q54IT0 (/ISS) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | O95707 (/IDA) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9CR08 (/ISO) |
|
Multimeric ribonuclease P complex GO:0030681
A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.
|
1 | O95707 (/IDA) |
|
Multimeric ribonuclease P complex GO:0030681
A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.
|
1 | Q9CR08 (/ISO) |
