The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 554: Uncharacterized protein, isoform B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
1 P48423 (/HMP)
Sister chromatid cohesion GO:0007062
The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
1 P48423 (/HMP)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
1 P48423 (/IMP)
Anterior/posterior axis specification, embryo GO:0008595
The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
1 P48423 (/TAS)
Female meiosis chromosome segregation GO:0016321
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.
1 P48423 (/HMP)
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
1 P48423 (/IGI)
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
1 P48423 (/IMP)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 P48423 (/IGI)
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
1 P48423 (/IMP)
Negative regulation of R7 cell differentiation GO:0045677
Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.
1 P48423 (/IGI)
Positive regulation of R7 cell differentiation GO:0045678
Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.
1 P48423 (/IGI)
Negative regulation of cell size GO:0045792
Any process that reduces cell size.
1 P48423 (/IMP)
Negative regulation of sevenless signaling pathway GO:0045873
Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.
1 P48423 (/IGI)
Negative regulation of torso signaling pathway GO:0120177
Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway.
1 P48423 (/IGI)
Negative regulation of torso signaling pathway GO:0120177
Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway.
1 P48423 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P48423 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...