The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Spermidine synthase, tetramerisation domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: SPE3p Spermidine synthase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spermidine synthase activity GO:0004766
Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
10 Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q99MI5 (/IMP)
Spermidine synthase activity GO:0004766
Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
5 P19623 (/IDA) P19623 (/IDA) P19623 (/IDA) P19623 (/IDA) Q99MI5 (/IDA)
Spermidine synthase activity GO:0004766
Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
4 P19623 (/TAS) P19623 (/TAS) P19623 (/TAS) P19623 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P19623 (/IPI) P19623 (/IPI) P19623 (/IPI) P19623 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 P19623 (/IPI) P19623 (/IPI) P19623 (/IPI) P19623 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 P19623 (/IDA) P19623 (/IDA) P19623 (/IDA) P19623 (/IDA)
Spermidine synthase activity GO:0004766
Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
3 Q09741 (/ISO) Q64674 (/ISO) Q64674 (/ISO)
Spermidine synthase activity GO:0004766
Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
3 G5EAU1 (/RCA) G5EAU1 (/RCA) G5EAU1 (/RCA)
Spermine synthase activity GO:0016768
Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
3 G5EAU1 (/RCA) G5EAU1 (/RCA) G5EAU1 (/RCA)
Spermidine synthase activity GO:0004766
Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
2 Q64674 (/ISS) Q64674 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q64674 (/ISO) Q64674 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q64674 (/ISO) Q64674 (/ISO)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Spermidine biosynthetic process GO:0008295
The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
15 F1R3G8 (/IMP) G5EAU1 (/IMP) G5EAU1 (/IMP) G5EAU1 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP)
(5 more)
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
9 Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP) Q12074 (/IMP)
Spermidine biosynthetic process GO:0008295
The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
5 P19623 (/IDA) P19623 (/IDA) P19623 (/IDA) P19623 (/IDA) Q99MI5 (/IDA)
Polyamine metabolic process GO:0006595
The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
4 P19623 (/TAS) P19623 (/TAS) P19623 (/TAS) P19623 (/TAS)
Arginine metabolic process GO:0006525
The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
3 G5EAU1 (/RCA) G5EAU1 (/RCA) G5EAU1 (/RCA)
Spermidine biosynthetic process GO:0008295
The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
3 Q09741 (/ISO) Q64674 (/ISO) Q64674 (/ISO)
Cellular response to farnesol GO:0097308
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
3 G5EAU1 (/IEP) G5EAU1 (/IEP) G5EAU1 (/IEP)
Spermidine biosynthetic process GO:0008295
The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
2 Q64674 (/ISS) Q64674 (/ISS)
Cellular response to leukemia inhibitory factor GO:1990830
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
2 Q64674 (/IEP) Q64674 (/IEP)
Pantothenate biosynthetic process GO:0015940
The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
1 Q09741 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 Q09741 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA) Q12074 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P19623 (/TAS) P19623 (/TAS) P19623 (/TAS) P19623 (/TAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
3 G5EAU1 (/IDA) G5EAU1 (/IDA) G5EAU1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q6FWB8 (/IDA) Q6FWB8 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q09741 (/HDA)
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