The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3: Neuraminidase 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
8 O35657 (/IDA) O35657 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99PW3 (/IDA)
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
8 A5PF10 (/ISS) A5PF10 (/ISS) A6BMK7 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O35657 (/IPI) O35657 (/IPI) Q99519 (/IPI) Q99519 (/IPI) Q99519 (/IPI) Q99519 (/IPI) Q99519 (/IPI) Q99PW3 (/IPI)
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
5 Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS)
Alpha-sialidase activity GO:0016997
Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.
5 Q99519 (/IMP) Q99519 (/IMP) Q99519 (/IMP) Q99519 (/IMP) Q99519 (/IMP)
Exo-alpha-sialidase activity GO:0004308
Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
2 O35657 (/ISO) O35657 (/ISO)
Alpha-sialidase activity GO:0016997
Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.
2 O35657 (/ISO) O35657 (/ISO)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Oligosaccharide catabolic process GO:0009313
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
11 A5PF10 (/ISS) A5PF10 (/ISS) A6BMK7 (/ISS) O35657 (/ISS) O35657 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS)
(1 more)
Glycosphingolipid metabolic process GO:0006687
The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
5 Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS)
Oligosaccharide catabolic process GO:0009313
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
5 Q99519 (/IMP) Q99519 (/IMP) Q99519 (/IMP) Q99519 (/IMP) Q99519 (/IMP)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
5 Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS)
Oligosaccharide catabolic process GO:0009313
The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
2 O35657 (/ISO) O35657 (/ISO)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
2 O35657 (/ISO) O35657 (/ISO)
Regulation of myoblast proliferation GO:2000291
Any process that modulates the frequency, rate or extent of myoblast proliferation.
2 O35657 (/ISO) O35657 (/ISO)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q99PW3 (/IMP)
Regulation of myoblast proliferation GO:2000291
Any process that modulates the frequency, rate or extent of myoblast proliferation.
1 Q99PW3 (/IMP)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
10 Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
10 Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q5JQI0 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
8 O35657 (/IDA) O35657 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99519 (/IDA) Q99PW3 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
8 A5PF10 (/ISS) A5PF10 (/ISS) A6BMK7 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS) Q5RAF4 (/ISS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS)
Specific granule lumen GO:0035580
The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
5 Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS)
Lysosomal lumen GO:0043202
The volume enclosed within the lysosomal membrane.
5 Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS) Q99519 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 Q99519 (/HDA) Q99519 (/HDA) Q99519 (/HDA) Q99519 (/HDA) Q99519 (/HDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2 O35657 (/ISO) O35657 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 O35657 (/ISO) O35657 (/ISO)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
2 O35657 (/ISO) O35657 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 O35657 (/ISO) O35657 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q99PW3 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...