The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Lipase, subunit A
".
FunFam 2: prokineticin-2 isoform X2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
4 | Q9HC23 (/TAS) Q9HC23 (/TAS) Q9QXU7 (/TAS) Q9QXU7 (/TAS) |
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
G protein-coupled receptor binding GO:0001664
Interacting selectively and non-covalently with a G protein-coupled receptor.
|
1 | Q8R413 (/IDA) |
There are 29 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
3 | Q863H5 (/ISS) Q9QXU7 (/ISS) Q9QXU7 (/ISS) |
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
3 | Q863H5 (/ISS) Q9QXU7 (/ISS) Q9QXU7 (/ISS) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
3 | Q863H5 (/ISS) Q9QXU7 (/ISS) Q9QXU7 (/ISS) |
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
3 | Q863H5 (/ISS) Q9QXU7 (/ISS) Q9QXU7 (/ISS) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
3 | Q863H5 (/ISS) Q9QXU7 (/ISS) Q9QXU7 (/ISS) |
Positive regulation of smooth muscle contraction GO:0045987
Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
|
3 | Q863H5 (/ISS) Q9QXU7 (/ISS) Q9QXU7 (/ISS) |
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
|
2 | Q9HC23 (/TAS) Q9HC23 (/TAS) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
2 | Q9HC23 (/IDA) Q9HC23 (/IDA) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
Epicardium-derived cardiac endothelial cell differentiation GO:0003349
The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
|
2 | Q9QXU7 (/TAS) Q9QXU7 (/TAS) |
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | Q9HC23 (/IDA) Q9HC23 (/IDA) |
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
|
2 | Q9HC23 (/NAS) Q9HC23 (/NAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
2 | Q9HC23 (/NAS) Q9HC23 (/NAS) |
G protein-coupled receptor signaling pathway GO:0007186
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
|
2 | Q9HC23 (/TAS) Q9HC23 (/TAS) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
2 | Q9HC23 (/TAS) Q9HC23 (/TAS) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | Q9HC23 (/IMP) Q9HC23 (/IMP) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
|
2 | Q9QXU7 (/IDA) Q9QXU7 (/IDA) |
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | Q9HC23 (/IDA) Q9HC23 (/IDA) |
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
|
2 | Q9HC23 (/TAS) Q9HC23 (/TAS) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
2 | Q9HC23 (/IDA) Q9HC23 (/IDA) |
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
Positive regulation of smooth muscle contraction GO:0045987
Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
|
2 | Q9HC23 (/IDA) Q9HC23 (/IDA) |
Positive regulation of smooth muscle contraction GO:0045987
Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
|
2 | Q9QXU7 (/ISO) Q9QXU7 (/ISO) |
Coronary vasculature development GO:0060976
The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.
|
2 | Q9QXU7 (/TAS) Q9QXU7 (/TAS) |
Vasculogenesis involved in coronary vascular morphogenesis GO:0060979
The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.
|
2 | Q9QXU7 (/TAS) Q9QXU7 (/TAS) |
Epicardium-derived cardiac vascular smooth muscle cell differentiation GO:0060983
The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
|
2 | Q9QXU7 (/TAS) Q9QXU7 (/TAS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q9HC23 (/TAS) Q9HC23 (/TAS) |