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CATH Superfamily 2.10.70.10

Complement Module, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Complement Module, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Membrane cofactor proteinComplement decay-accelerating factorComplement decay-accelerating factorComplement component C6Beta-2-glycoprotein 1Complement component C6Complement factor H-related protein 1Complement inhibitory factor HSC:2Fibronectin 1Fibronectin 1Fibronectin 1Collagen, type I, alpha 1Fibronectin 1fibronectin isoform X1fibronectin isoform X1fibronectin isoform X1Plasminogen activatorBeta-microseminoproteinSC:3CUB and Sushi multiple domains 3Seizure related 6 homolog likeMembrane cofactor proteinComplement factor b,-likemannan-binding lectin serine protease 1 isoform X2gamma-aminobutyric acid type B receptor subunit 1Complement C1r subcomponentMembrane cofactor proteinComplement C1s subcomponentsushi domain-containing protein 5Membrane cofactor proteinMannan-binding lectin serine protease 2Beta-2-glycoprotein 1Beta-2-glycoprotein 1Beta-2-glycoprotein 1Complement factor HBeta-2-glycoprotein 1Complement factor HComplement factor HComplement receptor type 2Interleukin-2 receptor subunit alphaSC:4HaptoglobinSelectin PVersican core proteinChordin-like 1, isoform CRA_cComplement receptor type 1Seizure related 6 homolog likeSeizure related 6 homolog likeCUB and sushi domain-containing protein 3 isoform ACYR61 isoform 1Mannan-binding lectin serine protease 1Fibronectin isoform X1protein kinase C-binding protein NELL2Sushi repeat-containing protein SRPXseizure 6-like protein 2 isoform X2Complement inhibitory factor HFibronectin 1Inactive serine protease PAMR1 isoform X1Sushi domain-containing protein 4sushi repeat-containing protein SRPX isoform X1Complement receptor type 1BMP-binding endothelial regulator proteinSeizure related 6 homologSushi repeat containing protein X-linkedBMP-binding endothelial regulator protein-likeComplement component receptor type 1seizure 6-like protein 2 isoform X2Complement factor HComplement component receptor type 1Pappalysin 1CUB and Sushi multiple domains 3von Willebrand factor C and EGF domain-containing proteinComplement factor BCUB and Sushi multiple domains 3Complement inhibitory factor HComplement decay-accelerating factor, GPI-anchoredCUB and Sushi multiple domains 3Pappalysin 1sushi repeat-containing protein SRPX2Thyroid peroxidaseComplement inhibitory factor HPappalysin 1CUB and Sushi multiple domains 3Sushi domain-containing protein 4Fibulin 7Coagulation factor XIII B chainCUB and sushi domain-containing protein 3 isoform X1CUB and Sushi multiple domains 3Pappalysin 1Complement component receptor type 1Complement C3d receptor 2CUB and Sushi multiple domains 3CUB and Sushi multiple domains 3Sushi repeat-containing protein SRPX2CUB and Sushi multiple domains 3Complement component C7Furrowed, isoform AComplement component C7Cellular communication network factor 6Uncharacterized protein, isoform AHig-anchoring scaffold protein, isoform AComplement component receptor type 1Uncharacterized protein, isoform BComplement component 4 binding protein betaHig-anchoring scaffold protein, isoform AUncharacterized protein, isoform BZona pellucida sperm-binding protein 3 receptorUncharacterized protein, isoform AComplement component 4 binding protein betaSeizure related 6 homologSR-CIuncharacterized protein LOC108094628 isoform X1Sushi domain containing 3Coagulation factor XIII B chainComplement component 4 binding protein betaSushi domain containing 2Complement factor H related 5Coagulation factor XIII B chainCoagulation factor XIII B chainUncharacterized protein, isoform BCoagulation factor XIII B chainUncharacterized protein, isoform CUncharacterized protein, isoform CUncharacterized protein, isoform BZona pellucida sperm-binding protein 3 receptorUncharacterized protein, isoform DUncharacterized protein, isoform AUncharacterized protein, isoform AUncharacterized protein, isoform ACoagulation factor XIII B chainSushi domain-containing protein 4Coagulation factor XIII B chainComplement factor H related 4Gamma-aminobutyric acid (GABA) B receptor, 1aComplement C1r subcomponent likeHig-anchoring scaffold protein, isoform AUncharacterized protein, isoform AUncharacterized protein, isoform AUncharacterized proteinUncharacterized protein, isoform BPredicted proteinUncharacterized protein, isoform CBlast:Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi domain-containing protein 4Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Coagulation factor XIII B chainCUB and sushi domain-containing protein 3 isoform X1Blast:Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Pappalysin 2Furrowed, isoform AUncharacterized protein, isoform ANeurogenic locus notch, putativeUncharacterized protein, isoform AComplement factor H related 5Uncharacterized protein, isoform AHig-anchoring scaffold protein, isoform AComplement component 1, r subcomponentUncharacterized proteinPredicted proteinReceptor protein-tyrosine kinaseFurrowed, isoform AMembrane cofactor proteinMembrane cofactor proteinSushi, von Willebrand factor type A, EGF and pentraxin domain containing 1C-type LECtinCysteine rich transmembrane BMP regulator 1Complement C1r subcomponent-like proteinUncharacterized proteinNeural EGFL like 2Uncharacterized proteinMannan-binding lectin serine peptidase 1Kielin/chordin-like proteinSushi, von Willebrand factor type A, EGF and pentraxin domain containing 1Complement factor H related 5Uncharacterized proteinSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Mannan-binding lectin associated serine protease 2C-type LECtinGG11343Hig-anchoring scaffold protein, isoform Csushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 isoform X2Furrowed, isoform BProclotting enzyme precursor, putativethyroid peroxidaseSushi, von Willebrand factor type A, EGF and pentraxin domain containing 1HaptoglobinUncharacterized proteinUncharacterized proteinSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Modular serine proteaseUncharacterized proteinFurrowed, isoform Akielin/chordin-like proteinFraser extracellular matrix complex subunit 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1CUB and sushi domain-containing protein 1Receptor tyrosine kinaseUncharacterized proteinMannose-binding lectin associated serine protease-3Complement factor b,-likeMannan-binding lectin serine peptidase 1Kielin/chordin-like proteinPredicted proteinUncharacterized proteinsushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 isoform X1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 isoform X4Uncharacterized proteinUncharacterized proteinComplement regulatory membrane proteinComplement regulatory membrane proteinComplement regulatory membrane proteinComplement regulatory membrane proteinComplement component receptor 1-like proteinCUB and sushi domain-containing protein 1Protein lev-9Protein lev-9Protein lev-9Protein lev-9Protein lev-9Protein lev-9Protein lev-9Uncharacterized proteinUncharacterized proteinSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Uncharacterized proteinUncharacterized proteinC-type LECtinUncharacterized proteinUncharacterized proteinMannose-binding lectin associated serine proteaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized protein, isoform BPeptidase domain-containing-associated with muscle regeneration 1Uncharacterized proteinComplement factor BComplement factor BUncharacterized proteinComplement factor BMannan-binding lectin serine peptidase 2Putative eel-fucolectin tachylectin-4 pentaxrin-1 domain proteinUncharacterized proteinSelectin Pfibropellin-1-like isoform X1Plasminogen activatorMannan-binding lectin serine peptidase 2Extracellular matrix protein FRAS1Uncharacterized proteinPxn-1Cellular communication network factor 5Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1Pappalysin 2Complement factor H-related 1CUB and sushi domain-containing protein 1Uncharacterized proteinUncharacterized proteinPredicted proteinComplement component 1, s subcomponentUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Uncharacterized proteinSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Predicted proteinUncharacterized proteinUncharacterized proteinSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinMannan binding lectin serine peptidase 2Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinComplement C1r subcomponent likeSushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1Uncharacterized proteinUncharacterized proteinLimulus clotting factor C, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPregnancy-associated plasma protein A, pappalysin 1bComplement factor B-like protease
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FunFam 19: Complement factor b,-like

GO Diversity

Unique GO annotations
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19 Unique GO terms

EC Diversity

Unique EC annotations
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3 Unique EC terms

Species Diversity

Unique species annotations
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39 Unique species

Statistics

Members
CATH Domains: 2
Sequences: 228
Annotations
Unique GO: 19
Unique EC: 3
Unique Species: 39
Representative
Rep ID: 3erbA03
Inherited Annotations: 0
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