The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
CD59
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 24: Cytotoxin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetylcholine receptor inhibitor activity GO:0030550
Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased.
7 B3EWF8 (/IDA) P86094 (/IDA) P86095 (/IDA) P86096 (/IDA) P86097 (/IDA) P86098 (/IDA) P86099 (/IDA)
Receptor antagonist activity GO:0048019
The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
1 Q8QGR0 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
7 P01446 (/IDA) P86094 (/IDA) P86095 (/IDA) P86096 (/IDA) P86097 (/IDA) P86098 (/IDA) P86099 (/IDA)
Modification of morphology or physiology of other organism GO:0035821
The process in which an organism effects a change in the structure or processes of a second organism.
1 B3EWF8 (/IDA)
Envenomation resulting in negative regulation of blood coagulation in other organism GO:0044470
A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism.
1 C0HJT5 (/IDA)
Negative regulation of signaling receptor activity GO:2000272
Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.
1 B3EWF8 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
8 C0HKZ8 (/IDA) P01446 (/IDA) P86094 (/IDA) P86095 (/IDA) P86096 (/IDA) P86097 (/IDA) P86098 (/IDA) P86099 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 B3EWF8 (/IDA)
Host cell postsynaptic membrane GO:0035792
A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.
1 B3EWF8 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...