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CATH Superfamily 2.10.220.10

Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Tyrosine-protein kinase receptorTyrosine-protein kinase receptorReceptor protein-tyrosine kinaseSC:2Receptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseReceptor tyrosine-protein kinase erbB-3SC:3R-spondin 3R-spondin 4Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseTyrosine-protein kinase receptorproprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 6Furin-like protease 2proprotein convertase subtilisin/kexin type 6proprotein convertase subtilisin/kexin type 5 isoform X2Furin, paired basic amino acid cleaving enzymeReceptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Tyrosine-protein kinase receptorFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Furin 2, isoform AProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Extracellular matrix protein FRAS1Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5bProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 4Proprotein convertase subtilisin/kexin type 5bProprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 6Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5proprotein convertase subtilisin/kexin type 6 isoform X1Proprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Furin-like protease 2Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Fraser extracellular matrix complex subunit 1Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 6 isoform PACE4-AI preproproteinExtracellular matrix protein FRAS1Furin 2, isoform DProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseFraser extracellular matrix complex subunit 1Erb-b2 receptor tyrosine kinase 3bGal/GalNAc lectin Igl2, putativeCXXC-rich proteinCXXC-rich, putativeHigh cysteine membrane protein TMK-likeFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5High cysteine membrane protein TMK-likeReceptor protein-tyrosine kinaseFurin-like protease 2Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5aUncharacterized proteinProprotein convertase subtilisin/kexin type 6R-spondin-3High cysteine membrane protein TMK-likeInsulin-like receptorFurin 2Fraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 6Furin-like protease 2Receptor protein-tyrosine kinaseTyrosine-protein kinase receptorReceptor protein-tyrosine kinaseReceptor protein-tyrosine kinaseFraser extracellular matrix complex subunit 1R-spondin 2Tyrosine-protein kinase receptorReceptor protein-tyrosine kinaseTyrosine-protein kinase receptorProprotein convertase subtilisin/kexin type 5aUncharacterized proteinFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5High cysteine membrane protein TMK-likeFurin2, putativeFurin-like protease 2Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin typePutative furin-like protease 2Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseErb-b2 receptor tyrosine kinase 3aFibronectin domain-containing proteinFurin-like protease 2R-spondin 1Endoprotease bli-4Tyrosine-protein kinase receptorProprotein convertase subtilisin/kexin type 5Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Uncharacterized proteinTyrosine-protein kinase receptorreceptor tyrosine-protein kinase erbB-4-likeProprotein convertase subtilisin/kexin type 5Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5aFraser extracellular matrix complex subunit 1Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Putative furin-like protease 2Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5R-spondin-3Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseProprotein convertase subtilisin/kexin type 5Receptor protein-tyrosine kinaseUncharacterized proteinHigh cysteine membrane protein Group 5Uncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5Fraser extracellular matrix complex subunit 1Uncharacterized proteinCXC-rich proteinProprotein convertase subtilisin/kexin type 5aReceptor protein-tyrosine kinaseUncharacterized proteinProprotein convertase subtilisin/kexin type 5Uncharacterized proteinTyrosine-protein kinase receptorUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 4Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Extracellular matrix protein FRAS1AGAP002915-PAUncharacterized proteinUncharacterized proteinUncharacterized proteinReceptor protein-tyrosine kinaseUncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5aPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5aUncharacterized proteinPredicted proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5Erb-b2 receptor tyrosine kinase 3aUncharacterized proteinProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5Predicted proteinReceptor protein-tyrosine kinaseUncharacterized proteinProprotein convertase subtilisin/kexin type 5aUncharacterized proteinPredicted proteinUncharacterized proteinProprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Proprotein convertase subtilisin/kexin type 5Uncharacterized proteinProprotein convertase subtilisin/kexin type 5Uncharacterized proteinErb-b2 receptor tyrosine kinase 3aProprotein convertase subtilisin/kexin type 5Extracellular matrix protein FRAS1Uncharacterized proteinFurin2, putativeProprotein convertase subtilisin/kexin type 4, furin, putativePredicted proteinProprotein convertase subtilisin/kexin type 5aProprotein convertase subtilisin/kexin type 5aPredicted protein
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FunFam 96: Furin-like protease 2

GO Diversity

Unique GO annotations
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4 Unique GO terms

EC Diversity

Unique EC annotations
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1 Unique EC terms

Species Diversity

Unique species annotations
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2 Unique species

Statistics

Members
CATH Domains: 0
Sequences: 3
Annotations
Unique GO: 4
Unique EC: 1
Unique Species: 2
Representative
Rep ID: P30432/1095-1148
Inherited Annotations: 0
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