The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cysteine Rich Protein
".
FunFam 89: LIM and SH3 domain protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
6 | Q14847 (/IPI) Q14847 (/IPI) Q14847 (/IPI) Q14847 (/IPI) Q61792 (/IPI) Q61792 (/IPI) |
|
Ion transmembrane transporter activity GO:0015075
Enables the transfer of an ion from one side of a membrane to the other.
|
6 | Q14847 (/ISS) Q14847 (/ISS) Q14847 (/ISS) Q14847 (/ISS) Q61792 (/ISS) Q61792 (/ISS) |
|
SH3/SH2 adaptor activity GO:0005070
Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
|
4 | Q14847 (/TAS) Q14847 (/TAS) Q14847 (/TAS) Q14847 (/TAS) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
4 | Q14847 (/HDA) Q14847 (/HDA) Q14847 (/HDA) Q14847 (/HDA) |
|
Ion transmembrane transporter activity GO:0015075
Enables the transfer of an ion from one side of a membrane to the other.
|
2 | Q61792 (/ISO) Q61792 (/ISO) |
|
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
2 | Q61792 (/IDA) Q61792 (/IDA) |
|
Ion transmembrane transporter activity GO:0015075
Enables the transfer of an ion from one side of a membrane to the other.
|
1 | Q99MZ8 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
6 | Q14847 (/ISS) Q14847 (/ISS) Q14847 (/ISS) Q14847 (/ISS) Q61792 (/ISS) Q61792 (/ISS) |
|
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q61792 (/ISO) Q61792 (/ISO) |
|
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q99MZ8 (/IDA) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | Q14847 (/IDA) Q14847 (/IDA) Q14847 (/IDA) Q14847 (/IDA) Q61792 (/IDA) Q61792 (/IDA) |
|
Cortical actin cytoskeleton GO:0030864
The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.
|
6 | Q14847 (/ISS) Q14847 (/ISS) Q14847 (/ISS) Q14847 (/ISS) Q61792 (/ISS) Q61792 (/ISS) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
4 | Q14847 (/HDA) Q14847 (/HDA) Q14847 (/HDA) Q14847 (/HDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | Q61792 (/ISO) Q61792 (/ISO) |
|
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
2 | Q61792 (/IDA) Q61792 (/IDA) |
|
Cortical actin cytoskeleton GO:0030864
The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.
|
2 | Q61792 (/ISO) Q61792 (/ISO) |
|
Cortical actin cytoskeleton GO:0030864
The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.
|
1 | Q99MZ8 (/IDA) |
