The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cysteine Rich Protein
".
FunFam 69: Uncharacterized protein, isoform Z
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Muscle alpha-actinin binding GO:0051371
Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
|
4 | B0WXP3 (/ISS) Q179D0 (/ISS) Q28WK7 (/ISS) Q7PTE3 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | G5EEL1 (/IPI) G5EFL5 (/IPI) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | A1ZA47 (/IPI) |
Actinin binding GO:0042805
Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin.
|
1 | A1ZA47 (/IPI) |
Muscle alpha-actinin binding GO:0051371
Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
|
1 | A1ZA47 (/IMP) |
Muscle alpha-actinin binding GO:0051371
Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
|
1 | A1ZA47 (/IPI) |
There are 20 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Regulation of cell-matrix adhesion GO:0001952
Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
|
4 | B0WXP3 (/ISS) Q179D0 (/ISS) Q28WK7 (/ISS) Q7PTE3 (/ISS) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
4 | G5EEF6 (/IMP) G5EEL1 (/IMP) G5EFG1 (/IMP) G5EFL5 (/IMP) |
Pharyngeal pumping GO:0043050
The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
|
4 | G5EEF6 (/IMP) G5EEL1 (/IMP) G5EFG1 (/IMP) G5EFL5 (/IMP) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | Q8MML5 (/IGI) |
Regulation of cell-matrix adhesion GO:0001952
Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
|
1 | A1ZA47 (/IMP) |
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
1 | Q8MML5 (/IMP) |
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
|
1 | Q8MML5 (/IMP) |
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | Q8MML5 (/IMP) |
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
|
1 | A1ZA47 (/IMP) |
Culmination involved in sorocarp development GO:0031154
The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
|
1 | Q8MML5 (/IMP) |
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
|
1 | Q8MML5 (/IMP) |
Locomotion GO:0040011
Self-propelled movement of a cell or organism from one location to another.
|
1 | Q8MML5 (/IMP) |
Chemotaxis to folate GO:0043326
The directed movement of a motile cell or organism in response to the presence of folate.
|
1 | Q8MML5 (/IMP) |
Chemotaxis to cAMP GO:0043327
The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
|
1 | Q8MML5 (/IMP) |
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
|
1 | Q8MML5 (/IMP) |
Cell motility GO:0048870
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
|
1 | Q8MML5 (/IMP) |
Negative regulation of phagocytosis GO:0050765
Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.
|
1 | Q8MML5 (/IMP) |
Muscle structure development GO:0061061
The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.
|
1 | A1ZA47 (/IMP) |
Midbody abscission GO:0061952
The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.
|
1 | Q8MML5 (/IMP) |
Regulation of actin cytoskeleton reorganization GO:2000249
Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
|
1 | Q8MML5 (/IMP) |
There are 16 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
4 | B0WXP3 (/ISS) Q179D0 (/ISS) Q28WK7 (/ISS) Q7PTE3 (/ISS) |
Striated muscle dense body GO:0055120
A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
|
4 | G5EEF6 (/IDA) G5EEL1 (/IDA) G5EFG1 (/IDA) G5EFL5 (/IDA) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
2 | A1ZA47 (/IDA) Q8MML5 (/IDA) |
Stress fiber GO:0001725
A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
|
1 | A1ZA47 (/IDA) |
Zonula adherens GO:0005915
A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
1 | A1ZA47 (/IDA) |
Muscle tendon junction GO:0005927
A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
|
1 | A1ZA47 (/IDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | A1ZA47 (/IDA) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
1 | A1ZA47 (/IDA) |
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
|
1 | A1ZA47 (/IDA) |
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
|
1 | Q8MML5 (/IDA) |
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
|
1 | A1ZA47 (/IDA) |
Filamentous actin GO:0031941
A two-stranded helical polymer of the protein actin.
|
1 | Q8MML5 (/IDA) |
Filopodium tip GO:0032433
The end of a filopodium distal to the body of the cell.
|
1 | Q8MML5 (/IDA) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
1 | Q8MML5 (/IDA) |
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
1 | A1ZA47 (/IDA) |
Basal part of cell GO:0045178
The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.
|
1 | A1ZA47 (/IDA) |