The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cysteine Rich Protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 190: LIM domain protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Rho GDP-dissociation inhibitor activity GO:0005094
Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
1 O74398 (/EXP)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lateral pseudopodium assembly GO:0031271
The extension of a pseudopodium from the lateral area of a cell.
1 Q54MG8 (/IMP)
Maintenance of actomyosin contractile ring localization GO:0032189
Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere.
1 O74398 (/IMP)
Actomyosin contractile ring organization GO:0044837
A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.
1 O74398 (/IMP)
Cell motility GO:0048870
Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
1 Q54MG8 (/IMP)
Positive regulation of mitotic division septum assembly GO:0140281
Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
1 O74398 (/IGI)
Regulation of mitotic actomyosin contractile ring contraction GO:1903471
Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
1 O74398 (/IMP)
Positive regulation of mitotic actomyosin contractile ring contraction GO:1903473
Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
1 O74398 (/IGI)
Regulation of mitotic actomyosin contractile ring assembly GO:1903499
Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
1 O74398 (/IGI)
Protein localization to mitotic actomyosin contractile ring GO:1904498
Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.
1 O74398 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Actomyosin contractile ring GO:0005826
A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.
1 O74398 (/IDA)
Medial cortex GO:0031097
A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
1 O74398 (/IDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 O74398 (/HDA)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 O74398 (/IDA)
Actomyosin contractile ring, intermediate layer GO:0120105
The region of the actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.
1 O74398 (/IDA)
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