View in Gene3D

CATH Superfamily 2.10.109.10

Umud Fragment, subunit A

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Umud Fragment, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2: Signal peptidase I

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
 29 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(19 more)
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
 21 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(11 more)
Endopeptidase activity GO:0004175
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Toxic substance binding GO:0015643
Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
 1 Q608M5 (/ISS)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Signal peptide processing GO:0006465
The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
 21 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(11 more)
Signal peptide processing GO:0006465
The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
 21 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(11 more)
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
 21 P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP) P00803 (/IMP)
(11 more)
Signal peptide processing GO:0006465
The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
 1 Q608M5 (/ISS)
Protein secretion GO:0009306
The controlled release of proteins from a cell.
 1 Q608M5 (/ISS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 21 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(11 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 21 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(11 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 21 P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA) P00803 (/IDA)
(11 more)
CATH-Gene3D is a Global Biodata Core Resource Learn more...