The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Geranylgeranyl transferase type-2 subunit betaGeranylgeranyl transferase type-1 subunit betaProtein farnesyltransferase subunit betaSC:2Terpene cyclase/mutase family memberProtein farnesyltransferase subunit betaSC:3Terpene cyclase/mutase family memberSC:4Complement C3Complement C4-ATranscobalamin-2Cobalamin binding intrinsic factorComplement C5Transcobalamin 1CD109 isoform 1Mannan endo-1,6-alpha-mannosidaseProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-2 subunit betaTerpene cyclase/mutase family memberGeranylgeranyl transferase type-2 subunit betaTerpene cyclase/mutase family memberProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-2 subunit betaAlpha-2-macroglobulinGeranylgeranyl transferase type-1 subunit betaTerpene cyclase/mutase family memberThioester-containing protein 4, isoform CGeranylgeranyl transferase type-2 subunit betaGeranylgeranyl transferase type-2 subunit betaSqualene--hopene cyclaseTerpene cyclase/mutase family memberGeranylgeranyl transferase type-2 subunit betaGeranylgeranyl transferase type-2 subunit betaGeranylgeranyl transferase type-2 subunit betaPutative geranylgeranyl transferase beta subunitMannan endo-1,6-alpha-mannosidaseCAAX geranylgeranyltransferase beta subunitProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaTerpene synthase family proteinComplement C4Fructose-bisphosphate aldolaseTerpenoid cyclases/protein prenyltransferase alpha-alpha toroidGeranylgeranyltransferase I beta subunit, putativeProtein farnesyltransferase subunit betaThioester-containing protein 6Lupeol synthasePrenyltransferase and squalene oxidase repeat family proteinProtein geranylgeranyltransferase type I subunit betaComplement 4B (Chido blood group)Putative cyclaseGeranylgeranyl transferase type-1 subunit betaPutative squalene-hopene cyclaseEnt-kaurene synthaseProtein farnesyltransferase subunit betaOs03g0193700 proteinBaccharis oxide synthaseTerpene cyclase/mutase family memberGlutinol synthaseTerpene cyclase/mutase family memberComplement C3Terpentedienyl-diphosphate synthaseTranscobalamin IIUncharacterized proteinProtein farnesyltransferase subunit betaUncharacterized proteinComplement component C3BGeranylgeranyl transferase type-1 subunit betaProtein CBG20759Protein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaMannan endo-1,6-alpha-mannosidaseMannan endo-1,6-alpha-mannosidaseUncharacterized proteinMannan endo-1,6-alpha-mannosidaseF3F9.1Protein farnesyltransferase subunit betaPrenyltransferase domain containing proteinProtein geranylgeranyltransferase type I subunitGeranylgeranyl transferase type II beta subunitProtein farnesyltransferase subunit betaMannan endo-1,6-alpha-mannosidaseUncharacterized proteinCycloartenol synthase 2Rab geranylgeranyltransferase subunit betaTerpene cyclase/mutase family memberCpras2, large protein with the cpRAS domainUbiquitin domain-containing proteinTerpene cyclase/mutase family memberTerpene cyclase/mutase family memberTerpene cyclase/mutase family memberComplement component 4A (Rodgers blood group)Terpene cyclase/mutase family memberTerpene synthase family protein (AFU_orthologue AFUA_5G15060)Terpene cyclase/mutase family memberUncharacterized proteinTerpene cyclase/mutase family memberUncharacterized proteinComplement component C5Pre-alpha-onocerin synthase LCCUncharacterized proteinMannan endo-1,6-alpha-mannosidaseUncharacterized proteinProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaGeranylgeranyl transferase type-2 subunit betaMeiotically up-regulated gene 191 proteinGeranylgeranyl transferase type-2 subunit betaUncharacterized proteinCAAX farnesyl transferaseUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinTranscobalamin IIGeranylgeranyl transferase type-2 subunit betaUncharacterized proteinUncharacterized proteinUncharacterized proteinFarnesyltransferase, CAAX box, betaUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGeranylgeranyl transferase type II beta subunit, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaProtein farnesyltransferase subunit betaUncharacterized proteinDammarenediol II synthaseUncharacterized proteinUncharacterized proteinUncharacterized proteinAlpha-onocerin synthase LCDDammarenediol II synthaseSqualene cyclase family proteinSqualene cyclase family proteinTerpene cyclase/mutase family memberTerpene cyclase/mutase family memberUncharacterized proteinTerpene cyclase/mutase family memberEnt-copalyl diphosphate synthaseUncharacterized proteinMurinoglobulin-2Terpene cyclase/mutase family member
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FunFam 22: Terpene cyclase/mutase family member

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cycloartenol synthase activity GO:0016871
Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.
5 A7BJ35 (/IDA) E2IUB0 (/IDA) O82139 (/IDA) Q2XPU6 (/IDA) Q6BE25 (/IDA)
Beta-amyrin synthase activity GO:0042300
Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin.
2 B6EXY6 (/IDA) B6EXY6 (/IDA)
Cucurbitadienol synthase activity GO:0034076
Catalysis of the reaction: oxidosqualene = cucurbitadienol.
1 Q6BE24 (/IDA)
Showing 1 to 3 of 3 entries

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Steroid biosynthetic process GO:0006694
The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
1 E2IUB0 (/IDA)
Tetracyclic triterpenoid biosynthetic process GO:0010686
The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
1 Q2XPU6 (/IDA)
Pentacyclic triterpenoid biosynthetic process GO:0019745
The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
1 O82139 (/IDA)
Showing 1 to 3 of 3 entries

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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