Glycoside hydrolase (GH) is a term for enzymes that catalyse the hydrolytic breakdown of the glycosidic linkages of glycosides, glycans, and glycoconjugates. GHs are distributed in almost all organisms.

This entry represents the GH144 family, which hydrolyses linear beta-1,2-glucan (a polysaccharide from Gram-negative bacteria, with important roles in infection and symbiosis). The structure of this enzyme has a large cavity appropriate for polysaccharide degradation and adopts an (alpha/alpha)6-fold slightly similar to that of GH family 15 and 8 enzymes PMID:28270506.