The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
Functional Families
Superfamily: AmiS/UreI transporter
The channel is closed at neutral pH and opens at acidic pH to allow the rapid access of urea to cytoplasmic urease PMID:23222544. UreI is a six-transmembrane segment protein that is homologous to the amiS genes of the amidase gene cluster and to UreI of Helicobacter hepaticus and Streptococcus salivarius PMID:12471160. The amiS gene encodes an 18kDa protein with a high content of hydrophobic residues. It has six transmembrane helices. AmiB and AmiS resemble two components of an ABC transporter system PMID:7642533.
This family includes UreI and proton gated urea channel as well as putative amide transporters PMID:10642549.
GO Diversity
EC Diversity
Species Diversity
Sequence/Structure Diversity
Superfamily Summary
| Structures | |
|---|---|
| Domains: | 15 |
| Domain clusters (>95% seq id): | 1 |
| Domain clusters (>35% seq id): | 1 |
| Unique PDBs: | 3 |
| Alignments | |
| Structural Clusters (5A): | 1 |
| Structural Clusters (9A): | 1 |
| FunFam Clusters: | 1 |
| Function | |
| Unique EC: | |
| Unique GO: | 2 |
| Taxonomy | |
| Unique Species: | 749 |
