The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: WD repeat-containing protein 19 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8NEZ3 (/IPI)

There are 33 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
5 A0A2R8RMT9 (/IMP) A0A2R8RPA6 (/IMP) E7FGG5 (/IMP) G5ECZ4 (/IMP) Q3UGF1 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
4 A0A2R8RMT9 (/IGI) A0A2R8RPA6 (/IGI) E7FGG5 (/IGI) Q3UGF1 (/IGI)
Intraciliary retrograde transport GO:0035721
The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
2 G5ECZ4 (/IMP) Q8NEZ3 (/IMP)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
1 Q3UGF1 (/IMP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 Q3UGF1 (/IMP)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 G5ECZ4 (/IMP)
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
1 Q3UGF1 (/IMP)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 G5ECZ4 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
1 G5ECZ4 (/IMP)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
1 Q3UGF1 (/IMP)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
1 Q3UGF1 (/IMP)
Embryonic camera-type eye development GO:0031076
The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
1 Q3UGF1 (/IMP)
Intraciliary retrograde transport GO:0035721
The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
1 Q3UGF1 (/ISO)
Intraciliary transport involved in cilium assembly GO:0035735
The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
1 Q8NEZ3 (/TAS)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 G5ECZ4 (/IMP)
Intraciliary transport GO:0042073
The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
1 G5ECZ4 (/IDA)
Ear morphogenesis GO:0042471
The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
1 Q3UGF1 (/IMP)
Embryonic cranial skeleton morphogenesis GO:0048701
The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
1 Q3UGF1 (/IMP)
Nervous system process GO:0050877
A organ system process carried out by any of the organs or tissues of neurological system.
1 Q3UGF1 (/IMP)
Digestive system development GO:0055123
The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
1 Q3UGF1 (/IMP)
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 Q3UGF1 (/ISO)
Ciliary receptor clustering involved in smoothened signaling pathway GO:0060830
Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.
1 Q3UGF1 (/IGI)
Smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
1 Q3UGF1 (/IGI)
Smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831
The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
1 Q3UGF1 (/IMP)
Myotome development GO:0061055
The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.
1 Q3UGF1 (/IMP)
Protein localization to cilium GO:0061512
A process in which a protein is transported to, or maintained in, a location within a cilium.
1 Q3UGF1 (/ISO)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 Q8NEZ3 (/IMP)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 Q3UGF1 (/ISO)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
1 Q3UGF1 (/ISS)
Protein localization to ciliary membrane GO:1903441
A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
1 Q8NEZ3 (/IMP)
Protein localization to ciliary membrane GO:1903441
A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
1 Q3UGF1 (/ISO)
Protein localization to ciliary membrane GO:1903441
A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
1 Q3UGF1 (/ISS)
Non-motile cilium assembly GO:1905515
The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.
1 G5ECZ4 (/IMP)

There are 17 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Intraciliary transport particle A GO:0030991
The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.
2 Q3UGF1 (/IDA) Q8NEZ3 (/IDA)
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
2 G5ECZ4 (/IDA) Q3UGF1 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q8NEZ3 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q3UGF1 (/ISO)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q3UGF1 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q8NEZ3 (/TAS)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q8NEZ3 (/IDA)
Nuclear body GO:0016604
Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
1 Q3UGF1 (/ISO)
Intraciliary transport particle A GO:0030991
The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.
1 Q3UGF1 (/ISO)
Intraciliary transport particle A GO:0030991
The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.
1 Q3UGF1 (/ISS)
Intraciliary transport particle B GO:0030992
The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.
1 G5ECZ4 (/IDA)
Motile cilium GO:0031514
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
1 Q3UGF1 (/IDA)
Motile cilium GO:0031514
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
1 Q8NEZ3 (/ISS)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
1 Q3UGF1 (/IDA)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
1 Q8NEZ3 (/ISS)
Ciliary tip GO:0097542
Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
1 Q8NEZ3 (/TAS)
Non-motile cilium GO:0097730
A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
1 Q8NEZ3 (/ISS)
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