The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
ARM repeat; domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Eukaryotic translation initiation factor 3 subunit...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
15 Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI) Q9UBQ5 (/IPI)
(5 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9DBZ5 (/RCA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
20 Q28C65 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS)
(10 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
16 Q9DBZ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA)
(6 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
15 Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC) Q9UBQ5 (/IC)
(5 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
15 Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS)
(5 more)
Translational initiation GO:0006413
The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
1 Q9DBZ5 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Eukaryotic translation initiation factor 3 complex GO:0005852
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
20 Q28C65 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS) Q3T0V3 (/ISS)
(10 more)
Eukaryotic translation initiation factor 3 complex GO:0005852
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
16 Q9DBZ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA)
(6 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA) Q9UBQ5 (/IDA)
(5 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
15 Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS) Q9UBQ5 (/TAS)
(5 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
15 Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA) Q9UBQ5 (/HDA)
(5 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9W2D9 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9DBZ5 (/ISO)
Eukaryotic translation initiation factor 3 complex GO:0005852
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
1 Q9DBZ5 (/ISO)
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