The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ankyrin repeat-containing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 803: Transient receptor potential cation channel protei...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
1 Q9W0Y6 (/TAS)
Calcium activated cation channel activity GO:0005227
Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.
1 Q9W0Y6 (/IDA)
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
1 Q9W0Y6 (/IDA)
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
1 Q9W0Y6 (/ISS)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9W0Y6 (/ISS)
Copulation GO:0007620
The act of sexual union between male and female, involving the transfer of sperm.
1 Q9W0Y6 (/IMP)
Feeding behavior GO:0007631
Behavior associated with the intake of food.
1 Q9W0Y6 (/IMP)
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
1 Q9W0Y6 (/IMP)
Regulation of heart contraction GO:0008016
Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
1 Q9W0Y6 (/IMP)
Male courtship behavior GO:0008049
The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
1 Q9W0Y6 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9W0Y6 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9W0Y6 (/TAS)
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
1 Q9W0Y6 (/NAS)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
1 Q9W0Y6 (/IMP)
Larval turning behavior GO:0035179
Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.
1 Q9W0Y6 (/IMP)
Olfactory behavior GO:0042048
The behavior of an organism in response to an odor.
1 Q9W0Y6 (/IMP)
Regulation of female receptivity GO:0045924
Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.
1 Q9W0Y6 (/IMP)
Negative gravitaxis GO:0048060
The directed movement of a motile cell or organism away from the source of gravity.
1 Q9W0Y6 (/IMP)
Behavioral response to pain GO:0048266
Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
1 Q9W0Y6 (/IMP)
Detection of temperature stimulus involved in thermoception GO:0050960
The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.
1 Q9W0Y6 (/IDA)
Detection of temperature stimulus involved in thermoception GO:0050960
The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.
1 Q9W0Y6 (/IMP)
Detection of temperature stimulus involved in sensory perception of pain GO:0050965
The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.
1 Q9W0Y6 (/IMP)
Detection of mechanical stimulus involved in sensory perception of pain GO:0050966
The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
1 Q9W0Y6 (/IMP)
Detection of mechanical stimulus involved in sensory perception GO:0050974
The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.
1 Q9W0Y6 (/TAS)
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
1 Q9W0Y6 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9W0Y6 (/HDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9W0Y6 (/NAS)
Calcium channel complex GO:0034704
An ion channel complex through which calcium ions pass.
1 Q9W0Y6 (/IDA)
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