The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ankyrin repeat-containing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 72: Ankyrin repeat and LEM domain containing 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphatase 2A binding GO:0051721
Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q86XL3 (/IPI)
Protein phosphatase regulator activity GO:0019888
Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
1 Q86XL3 (/TAS)
Protein phosphatase 2A binding GO:0051721
Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.
1 Q86XL3 (/IDA)
Protein phosphatase 2A binding GO:0051721
Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.
1 Q6P1H6 (/ISO)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
3 Q8MQX9 (/IMP) Q9VX44 (/IMP) X2JCC5 (/IMP)
Mitotic nuclear envelope reassembly GO:0007084
The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Negative regulation of phosphorylation GO:0042326
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Mitotic nuclear envelope reassembly GO:0007084
The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
1 Q86XL3 (/IMP)
Mitotic nuclear envelope reassembly GO:0007084
The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
1 Q6P1H6 (/ISO)
Mitotic nuclear envelope reassembly GO:0007084
The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
1 Q86XL3 (/TAS)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 Q86XL3 (/IDA)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 Q6P1H6 (/ISO)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
1 Q86XL3 (/IDA)
Positive regulation of protein dephosphorylation GO:0035307
Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
1 Q6P1H6 (/ISO)
Negative regulation of phosphorylation GO:0042326
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
1 Q86XL3 (/IDA)
Negative regulation of phosphorylation GO:0042326
Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
1 Q6P1H6 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q86XL3 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q6P1H6 (/ISO)
Regulation of catalytic activity GO:0050790
Any process that modulates the activity of an enzyme.
1 Q86XL3 (/TAS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q8MQX9 (/IDA) Q9VX44 (/IDA) X2JCC5 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
3 Q8MQX9 (/IDA) Q9VX44 (/IDA) X2JCC5 (/IDA)
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
3 Q8MQX9 (/HDA) Q9VX44 (/HDA) X2JCC5 (/HDA)
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 Q6P1H6 (/ISS) Q7TP65 (/ISS)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
1 Q86XL3 (/TAS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q86XL3 (/HDA)
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q86XL3 (/IDA)
Integral component of endoplasmic reticulum membrane GO:0030176
The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6P1H6 (/ISO)
CATH-Gene3D is a Global Biodata Core Resource Learn more...