The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ankyrin repeat-containing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 627: Ankyrin repeat and LEM domain containing 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
1 Q8NAG6 (/IDA)
Endonuclease activity GO:0004519
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
1 A8VU90 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8NAG6 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
1 Q8NAG6 (/IDA)
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
1 Q8NAG6 (/IMP)
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
1 A8VU90 (/ISO)
Negative regulation of mitotic recombination GO:0045950
Any process that inhibits or decreases the rate of DNA recombination during mitosis.
1 A8VU90 (/IGI)
Nucleic acid phosphodiester bond hydrolysis GO:0090305
The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
1 Q8NAG6 (/IC)
Regulation of myeloid progenitor cell differentiation GO:1905453
Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.
1 A8VU90 (/IMP)
Regulation of lymphoid progenitor cell differentiation GO:1905456
Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.
1 A8VU90 (/IMP)
Positive regulation of response to DNA damage stimulus GO:2001022
Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.
1 Q8NAG6 (/IDA)
Positive regulation of response to DNA damage stimulus GO:2001022
Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.
1 A8VU90 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8NAG6 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 A8VU90 (/ISO)
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