The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Ankyrin repeat-containing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 57: Ankyrin repeat domain-containing protein 13B

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-dependent protein binding GO:0140036
Interacting selectively and non-covalently with a protein upon ubiquitination of the target protein.
6 Q86YJ7 (/IDA) Q86YJ7 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA)
Ubiquitin-dependent protein binding GO:0140036
Interacting selectively and non-covalently with a protein upon ubiquitination of the target protein.
6 Q86YJ7 (/IPI) Q86YJ7 (/IPI) Q8IZ07 (/IPI) Q8IZ07 (/IPI) Q8IZ07 (/IPI) Q8IZ07 (/IPI)
Ubiquitin-dependent protein binding GO:0140036
Interacting selectively and non-covalently with a protein upon ubiquitination of the target protein.
3 Q5F259 (/ISO) Q6PD24 (/ISO) Q80UP5 (/ISO)
Ubiquitin-dependent protein binding GO:0140036
Interacting selectively and non-covalently with a protein upon ubiquitination of the target protein.
3 Q5F259 (/ISS) Q6PD24 (/ISS) Q80UP5 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of receptor internalization GO:0002091
Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.
6 Q86YJ7 (/IMP) Q86YJ7 (/IMP) Q8IZ07 (/IMP) Q8IZ07 (/IMP) Q8IZ07 (/IMP) Q8IZ07 (/IMP)
Negative regulation of protein localization to endosome GO:1905667
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
4 Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA)
Negative regulation of receptor internalization GO:0002091
Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.
3 Q5F259 (/ISO) Q6PD24 (/ISO) Q80UP5 (/ISO)
Negative regulation of receptor internalization GO:0002091
Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.
3 Q5F259 (/ISS) Q6PD24 (/ISS) Q80UP5 (/ISS)
Negative regulation of protein localization to endosome GO:1905667
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
1 Q80UP5 (/ISO)
Negative regulation of protein localization to endosome GO:1905667
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
1 Q80UP5 (/ISS)

There are 18 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
10 Q3ZTS7 (/IDA) Q3ZTS7 (/IDA) Q3ZTS7 (/IDA) Q3ZTS7 (/IDA) Q86YJ7 (/IDA) Q86YJ7 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q86YJ7 (/IDA) Q86YJ7 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
6 Q86YJ7 (/IDA) Q86YJ7 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
6 Q86YJ7 (/IDA) Q86YJ7 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA) Q8IZ07 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
4 A0A024QZ29 (/IDA) A0A024QZ29 (/IDA) Q86YJ7 (/IDA) Q86YJ7 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 A8DYI9 (/HDA) Q7K4M9 (/HDA) Q8IGB6 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q5F259 (/ISO) Q6PD24 (/ISO) Q80UP5 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q5F259 (/ISS) Q6PD24 (/ISS) Q80UP5 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q5F259 (/ISO) Q6PD24 (/ISO) Q80UP5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q5F259 (/ISS) Q6PD24 (/ISS) Q80UP5 (/ISS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 Q5F259 (/ISO) Q6PD24 (/ISO) Q80UP5 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 Q5F259 (/ISS) Q6PD24 (/ISS) Q80UP5 (/ISS)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
2 Q86YJ7 (/IDA) Q86YJ7 (/IDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2 Q5F259 (/ISO) Q80UP5 (/ISO)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2 Q5F259 (/ISS) Q80UP5 (/ISS)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 Q5F259 (/ISO)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
1 Q5F259 (/ISS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q5F259 (/ISO)
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