The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Ankyrin repeat-containing domain
".
FunFam 23: short transient receptor potential channel 4 isofo...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | Q9QUQ5 (/IPI) Q9QUQ5 (/IPI) Q9QX29 (/IPI) Q9QX29 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) |
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
4 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) Q9QX29 (/ISO) Q9QX29 (/ISO) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
4 | Q9UBN4 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) |
Store-operated calcium channel activity GO:0015279
A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
|
4 | Q9UBN4 (/IMP) Q9UBN4 (/IMP) Q9UBN4 (/IMP) Q9UBN4 (/IMP) |
Store-operated calcium channel activity GO:0015279
A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
|
4 | Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) |
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
4 | Q9UBN4 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) Q9UBN4 (/IPI) |
Inositol 1,4,5 trisphosphate binding GO:0070679
Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate.
|
4 | Q9QUQ5 (/IDA) Q9QUQ5 (/IDA) Q9QX29 (/IDA) Q9QX29 (/IDA) |
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
2 | A0A0R4IM91 (/IDA) U3N7D8 (/IDA) |
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Store-operated calcium channel activity GO:0015279
A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Actinin binding GO:0042805
Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
1 | O35119 (/IDA) |
There are 19 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) |
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
|
4 | Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) |
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
4 | Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) |
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | A0A0R4IM91 (/IDA) U3N7D8 (/IDA) |
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Positive regulation of cytosolic calcium ion concentration GO:0007204
Any process that increases the concentration of calcium ions in the cytosol.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Positive regulation of peptidyl-threonine phosphorylation GO:0010800
Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Gamma-aminobutyric acid secretion GO:0014051
The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.
|
2 | Q9QUQ5 (/IMP) Q9QUQ5 (/IMP) |
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Positive regulation of axon extension GO:0045773
Any process that activates or increases the frequency, rate or extent of axon extension.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Oligodendrocyte differentiation GO:0048709
The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
|
2 | Q9QUQ5 (/IMP) Q9QUQ5 (/IMP) |
Negative regulation of dendrite morphogenesis GO:0050774
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
2 | A0A0R4IM91 (/IDA) U3N7D8 (/IDA) |
Regulation of calcium ion transport GO:0051924
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Calcium ion import GO:0070509
The directed movement of calcium ions into a cell or organelle.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Regulation of membrane hyperpolarization GO:1902630
Any process that modulates the frequency, rate or extent of membrane hyperpolarization.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O35119 (/IDA) |
Regulation of calcium ion transport GO:0051924
Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | O35119 (/IMP) |
There are 23 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | Q9QUQ5 (/IDA) Q9QUQ5 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) Q9QX29 (/ISO) Q9QX29 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) Q9UBN4 (/TAS) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
4 | Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
4 | Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) |
Cortical cytoskeleton GO:0030863
The portion of the cytoskeleton that lies just beneath the plasma membrane.
|
4 | Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) |
Calcium channel complex GO:0034704
An ion channel complex through which calcium ions pass.
|
4 | Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) Q9UBN4 (/IDA) |
Calcium channel complex GO:0034704
An ion channel complex through which calcium ions pass.
|
4 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) Q9QX29 (/ISO) Q9QX29 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Caveola GO:0005901
A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.
|
2 | Q9QUQ5 (/IDA) Q9QUQ5 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Growth cone GO:0030426
The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Cortical cytoskeleton GO:0030863
The portion of the cytoskeleton that lies just beneath the plasma membrane.
|
2 | Q9QUQ5 (/ISO) Q9QUQ5 (/ISO) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
2 | Q9QUQ5 (/IPI) Q9QUQ5 (/IPI) |
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Spanning component of plasma membrane GO:0044214
The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
|
2 | A0A0R4IM91 (/IDA) U3N7D8 (/IDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
2 | Q9QUQ5 (/IDA) Q9QUQ5 (/IDA) |
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
2 | Q9QX29 (/ISO) Q9QX29 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | O35119 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O35119 (/IDA) |