The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Ankyrin repeat-containing domain
".
FunFam 18: Transient receptor potential cation channel subfam...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 71 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | B3VP30 (/IPI) F1RIT1 (/IPI) O35433 (/IPI) Q704Y3 (/IPI) Q8NER1 (/IPI) Q9EPK8 (/IPI) Q9ERZ8 (/IPI) Q9HBA0 (/IPI) Q9WUD2 (/IPI) |
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
8 | A0A1D5PXA5 (/ISS) Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) Q9EPK8 (/ISS) Q9ERZ8 (/ISS) |
Cation channel activity GO:0005261
Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
|
6 | O35433 (/IDA) Q9ERZ8 (/IDA) Q9HBA0 (/IDA) Q9WTR1 (/IDA) Q9WTR1 (/IDA) Q9Y5S1 (/IDA) |
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Excitatory extracellular ligand-gated ion channel activity GO:0005231
Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
5 | Q9EPK8 (/IDA) Q9ERZ8 (/IDA) Q9HBA0 (/IDA) Q9WTR1 (/IDA) Q9WTR1 (/IDA) |
Calcium channel activity GO:0005262
Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
5 | B3VP30 (/IMP) F1RIT1 (/IMP) Q704Y3 (/IMP) Q9EPK8 (/IMP) Q9ERZ8 (/IMP) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Calcium-release channel activity GO:0015278
Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Phosphatidylinositol binding GO:0035091
Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Showing 1 to 10 of 71 entries
There are 187 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
6 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q9ERZ8 (/ISS) Q9HBA0 (/ISS) |
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
5 | B3VP30 (/IMP) F1RIT1 (/IMP) O35433 (/IMP) Q9ERZ8 (/IMP) Q9HBA0 (/IMP) |
Calcium ion transmembrane transport GO:0070588
A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Cellular response to alkaloid GO:0071312
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Cellular response to ATP GO:0071318
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Response to capsazepine GO:1901594
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
4 | A0A1J0M1I2 (/IMP) B0S711 (/IMP) B6RTA2 (/IMP) Q704Y3 (/IMP) |
Positive regulation of vascular permeability GO:0043117
Any process that increases the extent to which blood vessels can be pervaded by fluid.
|
4 | B2KN54 (/IMP) Q9EPK8 (/IMP) Q9ERZ8 (/IMP) Q9HBA0 (/IMP) |
Cellular response to acidic pH GO:0071468
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
|
4 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) |
Showing 1 to 10 of 187 entries
There are 69 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
10 | B3VP30 (/IDA) F1RIT1 (/IDA) O35433 (/IDA) Q704Y3 (/IDA) Q9EPK8 (/IDA) Q9HBA0 (/IDA) Q9WTR1 (/IDA) Q9WTR1 (/IDA) Q9WUD2 (/IDA) Q9Y5S1 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
5 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) Q8NER1 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | Q704Y3 (/ISO) Q9EPK8 (/ISO) Q9WTR1 (/ISO) Q9WTR1 (/ISO) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | A0A1D5PXA5 (/ISS) Q9EPK8 (/ISS) Q9ERZ8 (/ISS) Q9HBA0 (/ISS) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
4 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q704Y3 (/ISS) |
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
|
4 | Q697L1 (/ISS) Q6R5A3 (/ISS) Q6RX08 (/ISS) Q8NER1 (/ISS) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q8NER1 (/TAS) Q9HBA0 (/TAS) Q9Y5S1 (/TAS) |
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
|
3 | B3VP30 (/IDA) F1RIT1 (/IDA) Q9EPK8 (/IDA) |
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
3 | Q9ERZ8 (/IDA) Q9WTR1 (/IDA) Q9WTR1 (/IDA) |
Showing 1 to 10 of 69 entries